Epoxide ring opening in acid, base & neutral (Lewis acid) medium: basic concept & reaction mechanism
2 هزار بار بازدید -
5 سال پیش
-
#Epoxide,
#Epoxide, #Epoxideopening, #Lewisacid, #ringopening,
In this lecture, I have discussed the Epoxide ring-opening in acid, base & neutral (Lewis acid) medium: basic concept and complete reaction mechanism. I have discussed the selectivity of the opening of unsymmetrical epoxide which results in 1,2-disubstituted products in trans fashion like trans-1,2-diol. Additionally, I have discussed the epoxide to cyclic carbonate conversion using this methodology. The links for some related videos are given below. Audiences are requested to watch them.
For "Ethylene glycol (EG) preparation by Dr. Tanmoy Biswas (Chemistry : The Mystery of Molecules)." please click on the link "Ethylene glycol (EG) preparation by D..."
For "My Ph. D completion in Chemistry: Dr. Tanmoy Biswas." please click the link "My Ph. D completion in Chemistry: Dr...."
For "Boron enolate for preparation of active methylene compounds: mechanism & uniqueness of this reaction" please click on the link "Boron enolate for preparation of acti..."
For "Nature of Leaving Group in Nucleophilic substitution Reaction." please click on the link "Nature of Leaving Group in Nucleophil..."
For "Alkene oxidation into geminal-diol (cis) by Osmium tetroxide (OsO4): Basic concept and mechanism." please click on the link "Alkene oxidation into geminal-diol (c..."
For "Alkene oxidation to geminal-diol (cis) by cold, dilute, alkaline Potassium Permanganate (KMnO4)." please click the link "Alkene oxidation to vicinal-diol (cis..."
For "Corey-Chaykovsky reaction: preparation of epoxide using sulfur ylide: basic concept and mechanism." please click on the link "Corey-Chaykovsky reaction: preparatio..."
For "Contribution of Thrope-Ingold effect for Lactone stability & Epoxide preparation: complete mechanism" please click on the link "Contribution of Thrope-Ingold effect ..."
For "Epoxidation of alkene by peroxy acid (like m-CPBA): Basic concept & complete mechanism with examples" please click on the link "Prilezhaev Reaction: Epoxidation of a..."
For "Epoxidation of α,β-unsaturated carbonyl compounds using hydrogen peroxide and alkali." please click on the link "Epoxidation of α,β-unsaturated carbon..."
For "Epoxide ring opening in acid, base & neutral (Lewis acid) medium: basic concept & reaction mechanism" please click on the link "Epoxide ring opening in acid, base & ..."
For "Williamson Ether synthesis (Part 2): Limitation and Preparation of Cyclic Ethers (epoxide)." please click on the link "Williamson Ether synthesis (Part 2): ..."
For "Corey-Chaykovsky reaction: preparation of epoxide using sulfur ylide: basic concept and mechanism." please click on the link "Corey-Chaykovsky reaction: preparatio..."
For "Nucleophilic addition to Unsaturated carbon acting as an electrophile." please click on the link "Nucleophilic addition to Unsaturated ..."
For "Nucleophilicity or Nature of Nucleophile on Nucleophilic Substitution reaction." please click on the link "Nucleophilicity or Nature of Nucleoph..."
For "Nature of Leaving Group in Nucleophilic substitution Reaction." please click on the link "Nature of Leaving Group in Nucleophil..."
For "Carbocation: Factors guiding its stability." please click on the link "Carbocation: Factors guiding its stab..."
For "Tertiary Vs benzylic carbocation stability." please click on the link "Tertiary cation Vs benzylic carbo-cat..."
For "Why Hypercongugation cannot stabilize carbanion (M. O. Theory Explanation), a comparative study." please click on the link "Why Hyperconjugation cannot stabilize..."
For "MCQ-235: About Epoxide opening by Lewis acid by Dr. Tanmoy Biswas (Chemistry The Mystery of Molecule" please click on the link "MCQ-235: About Epoxide opening by Lew..."
For "Epoxide ring opening in acid, base & neutral (Lewis acid) medium: basic concept & reaction mechanism" please click on the link "Epoxide ring opening in acid, base & ..."
In this lecture, I have discussed the Epoxide ring-opening in acid, base & neutral (Lewis acid) medium: basic concept and complete reaction mechanism. I have discussed the selectivity of the opening of unsymmetrical epoxide which results in 1,2-disubstituted products in trans fashion like trans-1,2-diol. Additionally, I have discussed the epoxide to cyclic carbonate conversion using this methodology. The links for some related videos are given below. Audiences are requested to watch them.
For "Ethylene glycol (EG) preparation by Dr. Tanmoy Biswas (Chemistry : The Mystery of Molecules)." please click on the link "Ethylene glycol (EG) preparation by D..."
For "My Ph. D completion in Chemistry: Dr. Tanmoy Biswas." please click the link "My Ph. D completion in Chemistry: Dr...."
For "Boron enolate for preparation of active methylene compounds: mechanism & uniqueness of this reaction" please click on the link "Boron enolate for preparation of acti..."
For "Nature of Leaving Group in Nucleophilic substitution Reaction." please click on the link "Nature of Leaving Group in Nucleophil..."
For "Alkene oxidation into geminal-diol (cis) by Osmium tetroxide (OsO4): Basic concept and mechanism." please click on the link "Alkene oxidation into geminal-diol (c..."
For "Alkene oxidation to geminal-diol (cis) by cold, dilute, alkaline Potassium Permanganate (KMnO4)." please click the link "Alkene oxidation to vicinal-diol (cis..."
For "Corey-Chaykovsky reaction: preparation of epoxide using sulfur ylide: basic concept and mechanism." please click on the link "Corey-Chaykovsky reaction: preparatio..."
For "Contribution of Thrope-Ingold effect for Lactone stability & Epoxide preparation: complete mechanism" please click on the link "Contribution of Thrope-Ingold effect ..."
For "Epoxidation of alkene by peroxy acid (like m-CPBA): Basic concept & complete mechanism with examples" please click on the link "Prilezhaev Reaction: Epoxidation of a..."
For "Epoxidation of α,β-unsaturated carbonyl compounds using hydrogen peroxide and alkali." please click on the link "Epoxidation of α,β-unsaturated carbon..."
For "Epoxide ring opening in acid, base & neutral (Lewis acid) medium: basic concept & reaction mechanism" please click on the link "Epoxide ring opening in acid, base & ..."
For "Williamson Ether synthesis (Part 2): Limitation and Preparation of Cyclic Ethers (epoxide)." please click on the link "Williamson Ether synthesis (Part 2): ..."
For "Corey-Chaykovsky reaction: preparation of epoxide using sulfur ylide: basic concept and mechanism." please click on the link "Corey-Chaykovsky reaction: preparatio..."
For "Nucleophilic addition to Unsaturated carbon acting as an electrophile." please click on the link "Nucleophilic addition to Unsaturated ..."
For "Nucleophilicity or Nature of Nucleophile on Nucleophilic Substitution reaction." please click on the link "Nucleophilicity or Nature of Nucleoph..."
For "Nature of Leaving Group in Nucleophilic substitution Reaction." please click on the link "Nature of Leaving Group in Nucleophil..."
For "Carbocation: Factors guiding its stability." please click on the link "Carbocation: Factors guiding its stab..."
For "Tertiary Vs benzylic carbocation stability." please click on the link "Tertiary cation Vs benzylic carbo-cat..."
For "Why Hypercongugation cannot stabilize carbanion (M. O. Theory Explanation), a comparative study." please click on the link "Why Hyperconjugation cannot stabilize..."
For "MCQ-235: About Epoxide opening by Lewis acid by Dr. Tanmoy Biswas (Chemistry The Mystery of Molecule" please click on the link "MCQ-235: About Epoxide opening by Lew..."
For "Epoxide ring opening in acid, base & neutral (Lewis acid) medium: basic concept & reaction mechanism" please click on the link "Epoxide ring opening in acid, base & ..."
5 سال پیش
در تاریخ 1398/11/26 منتشر شده
است.
2,081
بـار بازدید شده