19.4a Formation of Hemiacetals and Acetals Addition of Alcohols | Organic Chemistry

Chad provides a comprehensive lesson on the nucleophilic addition of alcohols to aldehydes and ketones to produce hemiacetals and acetals.  He covers both the base catalyzed mechanism and the acid catalyzed mechanism including all arrow-pushing.  He makes a quick point of showing how glucose commonly forms a hemiacetal and then concludes the lesson showing how acetal formation is reversible with H3O+ and explaining how to predict the products of hydrolysis of acetals.

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00:00 Lesson Introduction
00:45 Base Catalyzed Addition of Alcohols (Formation of Hemiacetals)
02:29 Acid Catalyzed Addition of Alcohols (Formation of Hemiacetals and Acetals)
11:29 Glucose as a Hemiacetal
14:23 Hydrolysis of Acetals

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