Charlotte Thompson: Ankyrons: The future of target-binding reagents beyond antibodies

Ankyrons™ are next-generation target binding reagents provided by ProImmune that overcome many of the current constraints of research antibodies. They are highly stable recombinant single-domain binders that can be directly labelled or detected via an epitope or biotin tag. Ankyrons can be engineered to combine them with further Ankyron or other domains much more easily than even recombinant Antibodies. Unlike Antibodies, Ankyrons are never made in animals and do not have isotypes or any species origin.

Ankyron™ features:
   Single, highly-stable, small 15kD binding domain
   Always recombinant, monoclonal, sequence defined by default
   More than 1200 catalog target specificities; multiple clones per target typically; rapidly expanding range
   No more primaries: get any Ankyron with any of our tags or conjugates affordably to order
   No Fc- / Isotype background
   Selected entirely in vitro from our Teralibrary™ for higher affinity
   Unconstrained by immunological tolerance
   Highly thermostable
   Custom recombinant monoclonal generation for any budget*
   Further formatting to order as multi-specifics and multivalent molecules available
   More cost-effective than research antibody technology in every respect
   Generated without animal immunization
   Distinguish closely related proteins with Ankyron guided selection, such as pMHC, anti-id specific
   For research applications, including: flow cytometry, ELISA, western blotting, immunohistochemistry, immunoprecipitation, cell culture and more