Prokaryotic Translation TERMINATION - How do release factors work? Function of RFs, RF3, and RRF

theCrux
theCrux
3.5 هزار بار بازدید - 3 سال پیش - References/Resources:
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What is the process of translation termination in prokaryotes? How does a 70S ribosome terminate translation? What are the release factors involved in the termination process and how do they work? How does initiation factor 3 and EF-G elongation factor terminate translation? What is GGQ motif? Why is the current termination mechanism a bit false? Find out answers to all these questions in this video:
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00:00 Paused 70S complex
01:22 Release factors
04:53 Termination process (RF1)
06:37 RF3 binding
08:30 Ribosome recycling factor
09:20 EF-G pushes the RRF
10:47 IF3 helps release tRNA
11:50 Why is this mechanism wrong?

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