Comparison between Minor blood groups KELL,KIDD,DUFFY #bloodgroup #transfusion #biochemistry
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Hello viewers in this video
Hello viewers in this video we are going to see the minor blood groupa Kell, Kidd, duffy blood groups.
Kell Blood Group
The Kell blood group system is one of the major human blood group systems. It consists of over 25 antigens, the most significant of which are K (Kell) and k (cellano). The Kell antigens are proteins found on the surface of red blood cells. The presence or absence of these antigens can influence blood transfusions and hemolytic disease of the newborn (HDN). The Kell antigen (K) is relatively rare but highly immunogenic, meaning it can provoke an immune response if incompatible blood is transfused.
Kidd Blood Group
The Kidd blood group system includes three antigens: Jka, Jkb, and Jk3. These antigens are found on a protein that functions as a urea transporter in red blood cells. Kidd antibodies can cause delayed hemolytic transfusion reactions and HDN. The antibodies are often weak and can be challenging to detect, which is why the Kidd system is particularly significant in transfusion medicine.
Duffy Blood Group
The Duffy blood group system includes several antigens, most notably Fya and Fyb. The Duffy antigens are glycoproteins found on the surface of red blood cells and are also expressed in other tissues. Interestingly, the Duffy antigen acts as a receptor for the malaria parasite Plasmodium vivax, meaning individuals lacking Duffy antigens (Fy(a-b-)) are resistant to this type of malaria. In transfusion medicine, the Duffy antibodies can cause transfusion reactions and HDN.
These blood group systems are important for understanding transfusion compatibility, as well as for understanding certain disease resistances and susceptibilities.
Kell Blood Group
The Kell blood group system is one of the major human blood group systems. It consists of over 25 antigens, the most significant of which are K (Kell) and k (cellano). The Kell antigens are proteins found on the surface of red blood cells. The presence or absence of these antigens can influence blood transfusions and hemolytic disease of the newborn (HDN). The Kell antigen (K) is relatively rare but highly immunogenic, meaning it can provoke an immune response if incompatible blood is transfused.
Kidd Blood Group
The Kidd blood group system includes three antigens: Jka, Jkb, and Jk3. These antigens are found on a protein that functions as a urea transporter in red blood cells. Kidd antibodies can cause delayed hemolytic transfusion reactions and HDN. The antibodies are often weak and can be challenging to detect, which is why the Kidd system is particularly significant in transfusion medicine.
Duffy Blood Group
The Duffy blood group system includes several antigens, most notably Fya and Fyb. The Duffy antigens are glycoproteins found on the surface of red blood cells and are also expressed in other tissues. Interestingly, the Duffy antigen acts as a receptor for the malaria parasite Plasmodium vivax, meaning individuals lacking Duffy antigens (Fy(a-b-)) are resistant to this type of malaria. In transfusion medicine, the Duffy antibodies can cause transfusion reactions and HDN.
These blood group systems are important for understanding transfusion compatibility, as well as for understanding certain disease resistances and susceptibilities.
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در تاریخ 1403/03/09 منتشر شده
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