Famotidine Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses

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Famotidine

Generic Name: famotidine

Trade Name: Pepcid

Indication: short term treatment of active ulcer, GERD, treatment of heartburn, indigestion, management of Zollinger Ellison syndrome, prevention of GI bleeding in critically ill patients, management of symptoms associated with overuse of NSAIDs

Action: blocks action of histamine located in gastric parietal cells, inhibits gastric acid secretion

Therapeutic Class: antiulcer agent

Pharmacologic Class: Histamine H2 antagonist

Nursing Considerations:
 may cause arrythmias, agranulocytosis, aplastic anemias
 assess for abdominal pain and occult blood
 monitor CBC
 instruct pt to increase fluid and fiber intake to prevent constipation

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