Paracetamol (acetaminophen) pharmacology, clinical pharmacology lectures, pharmacology made easy
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2 ماه پیش
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paracetamol pharmacology, paracetamol pharmacology lecture,
paracetamol pharmacology, paracetamol pharmacology lecture, nsaids pharmacology lecture, acetaminophen pharmacology
Acetaminophen also known as paracetamol works in the central nervous system to decrease pain and fever, by reversibly inhibiting cyclooxygenase enzyme. Because it has little effect on peripheral prostaglandins, it is not used as an anti-inflammatory drug.
Paracetamol also does not affect platelet function or increase bleeding time. Acetaminophen is a great alternative to non-steroidal anti-inflammatory drug. Paracetamol is a first-line therapy for children with fever or pain, because aspirin is avoided due to risk of Reye’s syndrome. It is useful in patients with gastric complaints with NSAIDs and those who do not require the anti-inflammatory action of NSAIDs. Acetaminophen is also preferred for individuals with bleeding disorders, peptic ulcers, and aspirin allergies.
Dose of acetaminophen: It is used at a dose of 325 to 650 mg three to five times a day and the total adult dose of paracetamol per day is restricted to 2600 mg. At normal therapeutic doses, paracetamol has few significant adverse effects. With large doses of paracetamol, the available glutathione in the liver becomes depleted, which can lead to hepatic necrosis. N-acetyl cysteine is an antidote in cases of overdose.
Paracetamol has a boxed warning for hepatotoxicity, which can lead to liver failure. Patients with hepatic disease, viral hepatitis, or a history of alcoholism are at a higher risk of paracetamol-induced hepatotoxicity. Using alcohol also increases the risk of liver damage. Paracetamol should be avoided in patients with severe hepatic impairment.
Chapters:
0:00 - paracetamol (acetaminophen) pharmacology
0:11 - paracetamol (acetaminophen)
0:30 - paracetamol (acetaminophen) clinical indications
0:57 - dose of paracetamol (acetaminophen)
1:20 - paracetamol (acetaminophen) toxicity
1:29 - paracetamol (acetaminophen) poisoning treatment
1:35 - paracetamol (acetaminophen) boxed warning
1:51 - paracetamol (acetaminophen) and alcohol
paracetamol pharmacology, paracetamol pharmacology lecture, acetaminophen pharmacology, acetaminophen mechanism of action, paracetamol mechanism of action, tylenol mechanism of action, dose of paracetamol, paracetamol toxicity, paracetamol liver damage mechanism, paracetamol poisoning treatment, paracetamol boxed warning, paracetamol and alcohol, clinical pharmacology lectures, pharmacology made easy, nsaids pharmacology lecture, nsaids speed pharmacology,
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Disclaimer:
"Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition."
Acetaminophen also known as paracetamol works in the central nervous system to decrease pain and fever, by reversibly inhibiting cyclooxygenase enzyme. Because it has little effect on peripheral prostaglandins, it is not used as an anti-inflammatory drug.
Paracetamol also does not affect platelet function or increase bleeding time. Acetaminophen is a great alternative to non-steroidal anti-inflammatory drug. Paracetamol is a first-line therapy for children with fever or pain, because aspirin is avoided due to risk of Reye’s syndrome. It is useful in patients with gastric complaints with NSAIDs and those who do not require the anti-inflammatory action of NSAIDs. Acetaminophen is also preferred for individuals with bleeding disorders, peptic ulcers, and aspirin allergies.
Dose of acetaminophen: It is used at a dose of 325 to 650 mg three to five times a day and the total adult dose of paracetamol per day is restricted to 2600 mg. At normal therapeutic doses, paracetamol has few significant adverse effects. With large doses of paracetamol, the available glutathione in the liver becomes depleted, which can lead to hepatic necrosis. N-acetyl cysteine is an antidote in cases of overdose.
Paracetamol has a boxed warning for hepatotoxicity, which can lead to liver failure. Patients with hepatic disease, viral hepatitis, or a history of alcoholism are at a higher risk of paracetamol-induced hepatotoxicity. Using alcohol also increases the risk of liver damage. Paracetamol should be avoided in patients with severe hepatic impairment.
Chapters:
0:00 - paracetamol (acetaminophen) pharmacology
0:11 - paracetamol (acetaminophen)
0:30 - paracetamol (acetaminophen) clinical indications
0:57 - dose of paracetamol (acetaminophen)
1:20 - paracetamol (acetaminophen) toxicity
1:29 - paracetamol (acetaminophen) poisoning treatment
1:35 - paracetamol (acetaminophen) boxed warning
1:51 - paracetamol (acetaminophen) and alcohol
paracetamol pharmacology, paracetamol pharmacology lecture, acetaminophen pharmacology, acetaminophen mechanism of action, paracetamol mechanism of action, tylenol mechanism of action, dose of paracetamol, paracetamol toxicity, paracetamol liver damage mechanism, paracetamol poisoning treatment, paracetamol boxed warning, paracetamol and alcohol, clinical pharmacology lectures, pharmacology made easy, nsaids pharmacology lecture, nsaids speed pharmacology,
🔴 You can also show your support by following us on:
YouTube👉🏼: https://www.seevid.ir/fa/result?ytch=pharm...
Instagram👉🏼: Instagram: pharmacybyasim
Twitter👉🏼: Twitter: pharmed0929
Buy me a coffee👉🏼: https://www.buymeacoffee.com/pharmacy...
For any Queries and Suggestions Email on: [email protected]
Disclaimer:
"Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition."
2 ماه پیش
در تاریخ 1403/03/20 منتشر شده
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