Titration Curves of Aminoacids - Amrita University

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Alpha amino acids are the building blocks of proteins. Almost all proteins consist of various combinations of the same 20  amino acids. Amino acids are compounds containing both an amine group, -NH2, and a  carboxylic acid group, -COOH. In addition there is an "R" group which is different for each amino acid.

In physiological systems where the pH is near neutrality, the amino group of an
amino acid will be protonated and the carboxylic acid group will be unprotonated.

The acid-base behavior of amino acids is best described by Brønsted theory of acids and bases.A simple amino acid (that does not have an acid or base group in the "R" group) is a dibasic acid in its fully protonated form; it can donate two protons during its complete titration with a base.

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