WHAT IS THE MECHANISM OF BICALUTAMIDE

In this video, we explore the mechanism, clinical relevance, facts, and statistics related to Bicalutamide, a commonly prescribed anti-androgen drug for advanced prostate cancer. We discuss how Bicalutamide functions by binding to androgen receptors to inhibit testosterone and DHT action, critical for prostate cancer cell growth. A clinical scenario highlights a patient experiencing hot flashes—a side effect seen in 8-24% of patients—and the need for periodic liver function tests, given the drug's hepatic metabolism. We note that prostate cancer accounts for 21% of all new male cancer diagnoses and emphasize that while exact prescription numbers are not readily available, Bicalutamide is frequently used in advanced cases. For further information, resources from the National Cancer Institute and PubMed are recommended.

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