Beta Thalassemia - Causes and Types - minor, Major & Intermedia - Hematology
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Beta Thalassemia - Causes and
Beta Thalassemia - Causes and Types - minor, Major & Intermedia - Hematology.
Anemia is subdivided - based on MCV- into microcytic, normocytic and macrocytic anemia.
Microcytic anemia includes iron deficiency anemia (less iron), anemia of chronic disease (iron available but inaccessible), sideroblastic anemia (defect in heme synthesis) and thalassemia (defect in Globin synthesis).
Thalassemia comes from the Greek word "Thalassa" which means: the sea.
Beta thalassemia is common in Italy and Greece.
Symptoms of anemia are fatigue, pallor, shortness of breath, headache, dizziness, exercise intolerance, murmur (flow murmur, not organic), ischemia (angina pectoris).
It is subdivided into beta thalassemia major, beta thalassemia minor, and beta thalassemia intermedia.
The anemia is usually microcytic hypochromic. (Mean corpuscular volume "MCV" is low)
Hemoglobin is made up of heme and globin...Heme is made of iron plus protoporphyrin.
Chromosome 11 is involved, a non-sense DNA mutation leads to a premature stop codon formation which will cause termination of protein synthesis.
A defect in Beta globin chains synthesis leads to beta thalassemia.
Beta thalassemia can be usually diagnosed using hemoglobin electrophoresis.
Hair-on-end appearance can appear on an x-ray of the skull. (Radiological finding)
Beta thalassemia major is also known as Cooley's anemia.
Management of thalassemia is discussed in a different video.
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Disclaimer 1: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.
I am NOT a licensed physician…Talk to your doctor.
Disclaimer 2: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Get 90+ clinical vignettes on FACEBOOK Facebook: medicosis where you can directly message me…I respond to your messages personally. Thanks!
Whether you’re studying for the USMLE, MCAT, shelf exam, NCLEX, COMLEX, PLEB, MCCEE, AMC_CAT, PANCE,…etc., these videos will help! Take it to the bank :)
Watch my videos on
Alpha thalassemia Alpha Thalassemia - All You Need to K...
Lab results in thalassemia Thalassemia - Lab Results - How To Di...
Management of thalassemia Thalassemia - Treatment - Hematology ...
As always…Be safe, Stay happy and Study hard!
In brief, beta thalassemia is a microcytic, hemolytic anemia that affects people living near the mediterranean sea. If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
► Visit my website: https://www.medicosisperfectionalis.com/ My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/ 📱Save on your mobile phone bill: http://fbuy.me/q6bMj 🏦 Qbank (TrueLearn): https://truelearn.referralrock.com/l/...
Anemia is subdivided - based on MCV- into microcytic, normocytic and macrocytic anemia.
Microcytic anemia includes iron deficiency anemia (less iron), anemia of chronic disease (iron available but inaccessible), sideroblastic anemia (defect in heme synthesis) and thalassemia (defect in Globin synthesis).
Thalassemia comes from the Greek word "Thalassa" which means: the sea.
Beta thalassemia is common in Italy and Greece.
Symptoms of anemia are fatigue, pallor, shortness of breath, headache, dizziness, exercise intolerance, murmur (flow murmur, not organic), ischemia (angina pectoris).
It is subdivided into beta thalassemia major, beta thalassemia minor, and beta thalassemia intermedia.
The anemia is usually microcytic hypochromic. (Mean corpuscular volume "MCV" is low)
Hemoglobin is made up of heme and globin...Heme is made of iron plus protoporphyrin.
Chromosome 11 is involved, a non-sense DNA mutation leads to a premature stop codon formation which will cause termination of protein synthesis.
A defect in Beta globin chains synthesis leads to beta thalassemia.
Beta thalassemia can be usually diagnosed using hemoglobin electrophoresis.
Hair-on-end appearance can appear on an x-ray of the skull. (Radiological finding)
Beta thalassemia major is also known as Cooley's anemia.
Management of thalassemia is discussed in a different video.
💊🦠 Antibiotics Course: https://www.medicosisperfectionalis.c...
😍🖼Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/me...
Check out my playlist titled "Hematology/ Oncology"...https://goo.gl/KxAu6F
Disclaimer: I use affiliate links....
►👨🏫💊Antibiotics Lectures: https://www.medicosisperfectionalis.c... ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.c... and use the PROMO code: ELECTROLYTES50 to get a 50% discount.
Get all of my notes at Patreon: medicosis
Thanks for watching…
Please subscribe.
Don’t forget to check my recommended collection of the best medical books that I personally use https://www.amazon.com/shop/medicosis...
MEDICAL Sources that I use for my videos:-
► Goljan Rapid Review Pathology, https://amzn.to/2MufTPw
► Harrison’s Internal Medicine https://amzn.to/2OJiVNf
► Goldman-Cecil Medicine https://amzn.to/2N0v93u
► Davidson’s Principles and Practice of Medicine https://amzn.to/2vTmf1p
-------------------------------------------------------------------------
Many people ask me “How do you record your videos”?
Equipment that I use:-
► Apple iPad Pro https://amzn.to/2nKCyZW
► Apple pencil https://amzn.to/2PimMCc
►Iphone holder kit: https://amzn.to/2OVV3aj
►Rode Video Mic Go: https://amzn.to/2OVF4Je
►Rode SC7 3.5mm TRS to TRRS Patch Cable: https://amzn.to/2vu2WeY
►Extension Audio Cable https://amzn.to/2nIDApo
►Rode DDC-GO DeadCat Artificial Fur Wind Shield for VideoMic GO: https://amzn.to/2OpbV8m
Disclaimer 1: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.
I am NOT a licensed physician…Talk to your doctor.
Disclaimer 2: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Get 90+ clinical vignettes on FACEBOOK Facebook: medicosis where you can directly message me…I respond to your messages personally. Thanks!
Whether you’re studying for the USMLE, MCAT, shelf exam, NCLEX, COMLEX, PLEB, MCCEE, AMC_CAT, PANCE,…etc., these videos will help! Take it to the bank :)
Watch my videos on
Alpha thalassemia Alpha Thalassemia - All You Need to K...
Lab results in thalassemia Thalassemia - Lab Results - How To Di...
Management of thalassemia Thalassemia - Treatment - Hematology ...
As always…Be safe, Stay happy and Study hard!
In brief, beta thalassemia is a microcytic, hemolytic anemia that affects people living near the mediterranean sea. If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
► Visit my website: https://www.medicosisperfectionalis.com/ My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/ 📱Save on your mobile phone bill: http://fbuy.me/q6bMj 🏦 Qbank (TrueLearn): https://truelearn.referralrock.com/l/...
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در تاریخ 1396/07/13 منتشر شده
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