Know Your Body: Anaphylaxis Explained
8.8 هزار بار بازدید -
2 سال پیش
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We all know what allergies
We all know what allergies are, and many of us may also be familiar with the term, ‘anaphylaxis’. However, the reason why, and how, anaphylaxis occurs, may be less common knowledge. This video explores the immunoglobulin E-mediated (IgE) pathway, which is commonly activated during anaphylaxis. Subtopics highlighted in this video include what anaphylaxis is, how allergies develop, how anaphylaxis is triggered, and symptoms of anaphylaxis.
This video was made by McMaster University students Jasmine Sodhi, Sara Ukropina, Andy Zhu, and Arina Mojavery in collaboration with the Demystifying Medicine McMaster Program.
Copyright McMaster University 2022
References:
Aldakheel FM. (2021). Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics. International Journal of Environmental Research and Public Health. 18(22):12105. https://doi.org/10.3390/ijerph182212105
Church, M.K. (2016). Allergy, Histamine and Antihistamines. In: Hattori, Y., Seifert, R. (eds) Histamine and Histamine Receptors in Health and Disease. Handbook of Experimental Pharmacology, vol 241. Springer, Cham. Doi: 10.1007/164_2016_85
Gould, H.J., Sutton, B.J., Beavil, A.J., Beavil, R.L., McCloskey, N., Coker, H.A., Fear, D., Smurthwaite, L. (2003). The Biology of IgE and the Basis of Allergic Disease. Annu. Rev. Immunol, 21; 579-628. Doi: 10.1146/annurev.immunol.21.120601.141103
Janeway, C. A., Travers, P., & Walport, M. (2001). Immunobiology: The immune system in health and disease (5th ed.). Garland Publishing. Available from https://www.ncbi.nlm.nih.gov/books/NB...
John Hopkins Medicine. (n.d.). Allergies and the Immune System. https://www.hopkinsmedicine.org/healt...
Kemp, S.F., Lockey, R.F. (2002). Anaphylaxis: A review of causes and mechanisms. Journal of Allergy and Clinical Immunology, 110(3); 341-348. Doi: 10.1067/mai.2002.126811
Neural Activity. (2019, October 6. ALLERGIES/TYPE I HYPERSENSITIVITY. [Video]. YouTube. ALLERGIES/TYPE I HYPERSENSITIVITY
Profet, M. (1991). The function of allergy: Immunological defense against toxins. The Quarterly Review of Biology, 66(1); 23-62. Doi: 10.1086/417049
Sampson, H.A. (2003). Anaphylaxis and emergency treatment. Pediatrics, 2003(111); 1601-1608. PMID: 12777599
Siracusa, M.C., Kim, B.S., Spergel, J.M., Artis, D. (2013). Basophils and allergic inflammation. Journal of Allergy and Clinical Immunology, 132(4); 789-801. Doi: 10.1016/j.jaci.2013.07.046
Waserman, S., Bégin, P., Watson, W. (2018). IgE-mediated food allergy. Allergy, Asthma & Clinical Immunology, 14(55). Doi: 10.1186/s13223-018-0284-3
White, M.V. (1990). The role of histamine in allergic diseases. Journal of Allergy and Clinical Immunology, 86(4); 599-605. Doi: 10.1016/S0091-6749(05)80223-4
This video was made by McMaster University students Jasmine Sodhi, Sara Ukropina, Andy Zhu, and Arina Mojavery in collaboration with the Demystifying Medicine McMaster Program.
Copyright McMaster University 2022
References:
Aldakheel FM. (2021). Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics. International Journal of Environmental Research and Public Health. 18(22):12105. https://doi.org/10.3390/ijerph182212105
Church, M.K. (2016). Allergy, Histamine and Antihistamines. In: Hattori, Y., Seifert, R. (eds) Histamine and Histamine Receptors in Health and Disease. Handbook of Experimental Pharmacology, vol 241. Springer, Cham. Doi: 10.1007/164_2016_85
Gould, H.J., Sutton, B.J., Beavil, A.J., Beavil, R.L., McCloskey, N., Coker, H.A., Fear, D., Smurthwaite, L. (2003). The Biology of IgE and the Basis of Allergic Disease. Annu. Rev. Immunol, 21; 579-628. Doi: 10.1146/annurev.immunol.21.120601.141103
Janeway, C. A., Travers, P., & Walport, M. (2001). Immunobiology: The immune system in health and disease (5th ed.). Garland Publishing. Available from https://www.ncbi.nlm.nih.gov/books/NB...
John Hopkins Medicine. (n.d.). Allergies and the Immune System. https://www.hopkinsmedicine.org/healt...
Kemp, S.F., Lockey, R.F. (2002). Anaphylaxis: A review of causes and mechanisms. Journal of Allergy and Clinical Immunology, 110(3); 341-348. Doi: 10.1067/mai.2002.126811
Neural Activity. (2019, October 6. ALLERGIES/TYPE I HYPERSENSITIVITY. [Video]. YouTube. ALLERGIES/TYPE I HYPERSENSITIVITY
Profet, M. (1991). The function of allergy: Immunological defense against toxins. The Quarterly Review of Biology, 66(1); 23-62. Doi: 10.1086/417049
Sampson, H.A. (2003). Anaphylaxis and emergency treatment. Pediatrics, 2003(111); 1601-1608. PMID: 12777599
Siracusa, M.C., Kim, B.S., Spergel, J.M., Artis, D. (2013). Basophils and allergic inflammation. Journal of Allergy and Clinical Immunology, 132(4); 789-801. Doi: 10.1016/j.jaci.2013.07.046
Waserman, S., Bégin, P., Watson, W. (2018). IgE-mediated food allergy. Allergy, Asthma & Clinical Immunology, 14(55). Doi: 10.1186/s13223-018-0284-3
White, M.V. (1990). The role of histamine in allergic diseases. Journal of Allergy and Clinical Immunology, 86(4); 599-605. Doi: 10.1016/S0091-6749(05)80223-4
2 سال پیش
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