BRCA (Breast Cancer Gene) Positive? Learn Your Breast Cancer Risk & Much More. www.Ask2Me.org
3.9 هزار بار بازدید -
5 سال پیش
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We teach how to determine
We teach how to determine your personal risk for cancer if you carry any type of cancer causing gene mutation. The Ask2Me.org calculator was created by Harvard, MIT and the Dana-Farber Cancer Institute.
VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:
http://www.breastcancercourse.org
VISIT "ALL MUTATIONS KNOWN TO MAN EVALUATOR"
http://www.Ask2Me.org
LIST OF QUESTIONS FOR YOUR DOCTORS:
http://www.breastcancercourse.org/bre...
FOLLOW US:
Facebook: Facebook: Breast-Cancer-School-for-Patients-958519147618444
__________________________________
Questions for doctor if you carry a cancer causing muation:
1. What is my risk of developing cancer?
2. If I am older, isn't my risk less?
3. If I have a strong family history of cancer, is my risk higher?
4. If I have no family history of cancer, is my risk lower?
5. What is a Variant of Uncertain Significance?
6. Will you develop a screening and prevention plan for me?
7. Where else can I look for information about my mutation?
ASK2ME™
"Calculate the risk of cancers associated with gene mutations. Enter the age, the gene with a deleterious mutation, prior cancer history, and any prophylactic surgery. The results will best approximate the risk we have found in the literature."The purpose of the www.ask2me.org website is to display a reasonable approximation of the risk of cancers over time for various hereditary cancer susceptibility genes using ASK2ME™ (All Syndromes Known to Man Evaluator™). Many cancer susceptibility genes are now being tested for, and the risk of cancer with pathogenic mutations in some of these genes is not yet well disseminated. We have begun the process of finding reliable studies for each gene relative to its risk for each cancer in its spectrum. We have converted the results of these studies into clinically relevant absolute risk estimates. We will add genes, and update approximations as time and data permit."
This is a tool to help visualize recent data and is not meant to replace clinical judgement. We have worked hard to provide accurate and useful information, and document its sources, but we recognize that significant gaps in the literature still exist, and our estimates are subject to potentially significant changes. This website is a work in progress; we are constantly reviewing the latest literature to keep the information as accurate as possible. Please be sure to check this website often as risk estimates are frequently updated.The BRCA (Breast Cancer) gene is commonly referred to as “The Breast Cancer Gene.” If someone inherits a broken version of this gene (known as a “mutation”) at conception, they carry a significantly increased lifetime risk of breast cancer and ovarian cancer. This gene “mutation” can come from either their mother or father. Most breast cancers are not the result of BRCA mutations. In fact, it is estimated that BRCA and similar genetic mutations cause only 5 to 10% of all breast cancers."
Regarding BRCA Genetic Testing ("The Breast Cancer Gene")
Both men and women are at equal risk for carrying the BRCA mutation. Women are more commonly identified as “High Risk” for BRCA mutations because they may have been diagnosed with breast or ovarian cancer and are more often asked if they have a family history of these cancers. But it is important that men also learn if they are at high risk for cancer causing mutations and pursue genetic counseling. You may qualify for BRCA genetic testing if you have:
Below is a very simplified list of the most common qualifying risk factors.
*Breast cancer diagnosed at 50 or younger
*Ovarian cancer at any age
*A family member with a “BRCA mutation”
*A strong family history of breast, ovarian, prostate or pancreatic cancer
*Breast cancer in both breasts
*Male breast cancer at any age
*“Triple negative” breast cancer before age 60
*Ashkenazi Jewish ancestry and breast or pancreatic cancer
Multi-Gene Panel Testing
Although the majority of “hereditary” breast cancer is likely due to the BRCA genes, other gene mutations could be present that also cause an increased risk for breast and other types of cancers. “Multi-Gene Panel Tests” evaluate multiple other cancer-causing genes at the same time as BRCA testing. We recommend considering “Panel Testing” be included with BRCA testing. There is usually no additional cost for adding this test to BRCA genetic screening.
VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:
http://www.breastcancercourse.org
VISIT "ALL MUTATIONS KNOWN TO MAN EVALUATOR"
http://www.Ask2Me.org
LIST OF QUESTIONS FOR YOUR DOCTORS:
http://www.breastcancercourse.org/bre...
FOLLOW US:
Facebook: Facebook: Breast-Cancer-School-for-Patients-958519147618444
__________________________________
Questions for doctor if you carry a cancer causing muation:
1. What is my risk of developing cancer?
2. If I am older, isn't my risk less?
3. If I have a strong family history of cancer, is my risk higher?
4. If I have no family history of cancer, is my risk lower?
5. What is a Variant of Uncertain Significance?
6. Will you develop a screening and prevention plan for me?
7. Where else can I look for information about my mutation?
ASK2ME™
"Calculate the risk of cancers associated with gene mutations. Enter the age, the gene with a deleterious mutation, prior cancer history, and any prophylactic surgery. The results will best approximate the risk we have found in the literature."The purpose of the www.ask2me.org website is to display a reasonable approximation of the risk of cancers over time for various hereditary cancer susceptibility genes using ASK2ME™ (All Syndromes Known to Man Evaluator™). Many cancer susceptibility genes are now being tested for, and the risk of cancer with pathogenic mutations in some of these genes is not yet well disseminated. We have begun the process of finding reliable studies for each gene relative to its risk for each cancer in its spectrum. We have converted the results of these studies into clinically relevant absolute risk estimates. We will add genes, and update approximations as time and data permit."
This is a tool to help visualize recent data and is not meant to replace clinical judgement. We have worked hard to provide accurate and useful information, and document its sources, but we recognize that significant gaps in the literature still exist, and our estimates are subject to potentially significant changes. This website is a work in progress; we are constantly reviewing the latest literature to keep the information as accurate as possible. Please be sure to check this website often as risk estimates are frequently updated.The BRCA (Breast Cancer) gene is commonly referred to as “The Breast Cancer Gene.” If someone inherits a broken version of this gene (known as a “mutation”) at conception, they carry a significantly increased lifetime risk of breast cancer and ovarian cancer. This gene “mutation” can come from either their mother or father. Most breast cancers are not the result of BRCA mutations. In fact, it is estimated that BRCA and similar genetic mutations cause only 5 to 10% of all breast cancers."
Regarding BRCA Genetic Testing ("The Breast Cancer Gene")
Both men and women are at equal risk for carrying the BRCA mutation. Women are more commonly identified as “High Risk” for BRCA mutations because they may have been diagnosed with breast or ovarian cancer and are more often asked if they have a family history of these cancers. But it is important that men also learn if they are at high risk for cancer causing mutations and pursue genetic counseling. You may qualify for BRCA genetic testing if you have:
Below is a very simplified list of the most common qualifying risk factors.
*Breast cancer diagnosed at 50 or younger
*Ovarian cancer at any age
*A family member with a “BRCA mutation”
*A strong family history of breast, ovarian, prostate or pancreatic cancer
*Breast cancer in both breasts
*Male breast cancer at any age
*“Triple negative” breast cancer before age 60
*Ashkenazi Jewish ancestry and breast or pancreatic cancer
Multi-Gene Panel Testing
Although the majority of “hereditary” breast cancer is likely due to the BRCA genes, other gene mutations could be present that also cause an increased risk for breast and other types of cancers. “Multi-Gene Panel Tests” evaluate multiple other cancer-causing genes at the same time as BRCA testing. We recommend considering “Panel Testing” be included with BRCA testing. There is usually no additional cost for adding this test to BRCA genetic screening.
5 سال پیش
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