Transcription Factor Binding Sites | Locating Transcription Factor Binding Sites |
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Transcription Factor Binding Sites (TFBSs)Transcription
Transcription Factor Binding Sites (TFBSs)
Transcription factors are proteins with DNA binding activity that are involved in the regulation of transcription.
Generally, TFs modulate gene expression by binding to gene promoter regions or to distal regions called enhancers.
The distance between a TFBS and a transcription start site (TSS) of a gene regulated by the TF can be up to several megabases, and depends on the chromatin structure of the region.
Although by definition, TFs possess DNA binding domains, but also,...they may occasionally bind DNA indirectly, by interacting with another TF....
Transcription factors are proteins with DNA binding activity that are involved in the regulation of transcription.
Generally, TFs modulate gene expression by binding to gene promoter regions or to distal regions called enhancers.
The distance between a TFBS and a transcription start site (TSS) of a gene regulated by the TF can be up to several megabases, and depends on the chromatin structure of the region.
Although by definition, TFs possess DNA binding domains, but also,...they may occasionally bind DNA indirectly, by interacting with another TF....
3 سال پیش
در تاریخ 1400/06/23 منتشر شده
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