The Modified Starling Equation - made easy.
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11 ماه پیش
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There are serious limitations to
There are serious limitations to Starling principles taught in school. Newer understanding of edema formation has been there for many years but has not percolated in mainstream education. In this lecture, we discuss limitations of Starling principles and newer understanding of edema formation.
Good reads
1. https://derangedphysiology.com/main/c...
References :
1. Microvascular fluid exchange and the revised Starling principle. Cardiovasc Res. 2010 Jul 15;87(2):198-210.
2. The Role of the Lymphatic System in Heart Failure . Itkin et al. JACC VOL. 78, NO. 3, 2021:278–90 .
3. Signaling Mechanisms Regulating Endothelial Permeability DOLLY MEHTA AND ASRAR B. MALIK. Physiol Rev 86: 279–367, 2006.
4. Michel CC, Phillips ME. Steady-state fluid filtration at different capillary pressures in perfused frog mesenteric capillaries. J Physiol 1987;388:421–435.
5. Adamson RH, Lenz JF, Zhang X, Adamson GN, Weinbaum S, Curry FE. Oncotic pressures opposing filtration across non-fenestrated rat microvessels. J Physiol 2004;557:889 – 908.
6. Endothelial glycocalyx: basic science and clinical implications. Anaesth Intensive Care. 2017 May;45(3):295-307.
7. The Endothelial Glycocalyx: A Fundamental Determinant of Vascular Permeability in Sepsis. Jaime Fernández-Sarmiento. Pediatr Crit Care Med. 2020 May ; 21(5): e291–e300
8. Hu X, Adamson RH, Liu B, Curry FE, Weinbaum S. Starling forces that oppose filtration after tissue oncotic pressure is increased. Am J Physiol 2000;279: H1724 – H1736.
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Unless otherwise specified, these lectures are intended only for adult population and may not apply to pediatric/neonates.
Good reads
1. https://derangedphysiology.com/main/c...
References :
1. Microvascular fluid exchange and the revised Starling principle. Cardiovasc Res. 2010 Jul 15;87(2):198-210.
2. The Role of the Lymphatic System in Heart Failure . Itkin et al. JACC VOL. 78, NO. 3, 2021:278–90 .
3. Signaling Mechanisms Regulating Endothelial Permeability DOLLY MEHTA AND ASRAR B. MALIK. Physiol Rev 86: 279–367, 2006.
4. Michel CC, Phillips ME. Steady-state fluid filtration at different capillary pressures in perfused frog mesenteric capillaries. J Physiol 1987;388:421–435.
5. Adamson RH, Lenz JF, Zhang X, Adamson GN, Weinbaum S, Curry FE. Oncotic pressures opposing filtration across non-fenestrated rat microvessels. J Physiol 2004;557:889 – 908.
6. Endothelial glycocalyx: basic science and clinical implications. Anaesth Intensive Care. 2017 May;45(3):295-307.
7. The Endothelial Glycocalyx: A Fundamental Determinant of Vascular Permeability in Sepsis. Jaime Fernández-Sarmiento. Pediatr Crit Care Med. 2020 May ; 21(5): e291–e300
8. Hu X, Adamson RH, Liu B, Curry FE, Weinbaum S. Starling forces that oppose filtration after tissue oncotic pressure is increased. Am J Physiol 2000;279: H1724 – H1736.
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Unless otherwise specified, these lectures are intended only for adult population and may not apply to pediatric/neonates.
11 ماه پیش
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