Vitamin D Function and deficiency. Why is Vitamin D so important for you?
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2 سال پیش
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Vitamin D is a fat-soluble
Vitamin D is a fat-soluble vitamin which is required for absorption of calcium, magnesium, and phosphate.
One of the most important roles of vitamin D is to maintain skeletal calcium level, and control bone formation. But, Vitamin D also has a role in your nervous, muscle, and immune systems.
Many conflicting recent studies are now showing an association between vitamin D deficiency and cancer, cardiovascular disease, diabetes, autoimmune diseases, and depression.
low levels of vitamin D, also correlated with respiratory illnesses such as bronchitis and asthma, and symptoms including wheezing and chest tightness.
Vitamin D is produced by skin exposed to sunlight or obtained from dietary sources, including supplements.
Main source of vitamin D is Sunlight. About 50% to 90% of vitamin D is absorbed through the skin via sunlight while the rest comes from the diet.
Twenty minutes of sunshine daily with over 40% of skin exposed is required to prevent vitamin D deficiency.
Only a few foods, such as the flesh of fatty fish, naturally contain significant amounts of vitamin D.
Other foods also contain vitamins, but less amount. Beef liver, Cheese, Mushrooms, Egg yolks.
About 10 % of American population has Vitamin D deficiency.
The main cause of Vitamin D deficiency is Inadequate oral intake of calcium, and Limited sun exposure.
Aging, malabsorption and gastrointestinal diseases can also cause Vitamin D deficiency.
The majority of patients with vitamin D deficiency are asymptomatic. However, even mild chronic vitamin D deficiency can lead to chronic hypocalcemia and hyperparathyroidism, which can contribute risk of osteoporosis, falls and fractures, especially in the elderly population. Patients with a prolonged and severe vitamin D deficiency can experience symptoms associated with secondary hyperparathyroidism including bone pain, arthralgias, myalgias, fatigue, muscle twitching (fasciculations), and weakness. Fragility fractures may result from chronic vitamin D deficiency leading to osteoporosis. In children, irritability, lethargy, developmental delay, bone changes, or fractures can be symptoms of vitamin D deficiency.
Vitamin D supplementation can improve muscle strength and reduce fall frequency by approximately 50%.7 Thus, patients who have low bone mineral density or a prior low-impact (fragility) skeletal fracture and those at risk of falling should be evaluated for vitamin D deficiency to reduce the risk of all types of skeletal fractures.
Prevention
Adults less than 65 years of age who do not have year-round effective sun exposure shall consume 600 to 800 international units of vitamin D3 daily to prevent deficiency. Older adults 65 years of age or more shall consume 800 to 1000 international units of vitamin D3 daily to prevent deficiency and to reduce the risk of fractures and falls.
In case of deficiency, recommended doses are much higher.
For adults: Initial supplementation for 8 weeks with Vitamin D3 either 6,000 IU daily or 50,000 IU weekly can be considered.
Children who are vitamin D deficient require 2000 IU/day of vitamin D3 or 50,000 IU of vitamin D3 once weekly for 6 weeks.
By Laboratoires Servier - Smart Servier website: Images related to Fracture of femur (Thigh bone fracture), Bone fractures and Bones -- Download in Powerpoint format.Flickr: Images related to Fracture of femur (Thigh bone fracture), Bone fractures and Bones (in French)., CC BY-SA 3.0, https://commons.wikimedia.org/w/index...
One of the most important roles of vitamin D is to maintain skeletal calcium level, and control bone formation. But, Vitamin D also has a role in your nervous, muscle, and immune systems.
Many conflicting recent studies are now showing an association between vitamin D deficiency and cancer, cardiovascular disease, diabetes, autoimmune diseases, and depression.
low levels of vitamin D, also correlated with respiratory illnesses such as bronchitis and asthma, and symptoms including wheezing and chest tightness.
Vitamin D is produced by skin exposed to sunlight or obtained from dietary sources, including supplements.
Main source of vitamin D is Sunlight. About 50% to 90% of vitamin D is absorbed through the skin via sunlight while the rest comes from the diet.
Twenty minutes of sunshine daily with over 40% of skin exposed is required to prevent vitamin D deficiency.
Only a few foods, such as the flesh of fatty fish, naturally contain significant amounts of vitamin D.
Other foods also contain vitamins, but less amount. Beef liver, Cheese, Mushrooms, Egg yolks.
About 10 % of American population has Vitamin D deficiency.
The main cause of Vitamin D deficiency is Inadequate oral intake of calcium, and Limited sun exposure.
Aging, malabsorption and gastrointestinal diseases can also cause Vitamin D deficiency.
The majority of patients with vitamin D deficiency are asymptomatic. However, even mild chronic vitamin D deficiency can lead to chronic hypocalcemia and hyperparathyroidism, which can contribute risk of osteoporosis, falls and fractures, especially in the elderly population. Patients with a prolonged and severe vitamin D deficiency can experience symptoms associated with secondary hyperparathyroidism including bone pain, arthralgias, myalgias, fatigue, muscle twitching (fasciculations), and weakness. Fragility fractures may result from chronic vitamin D deficiency leading to osteoporosis. In children, irritability, lethargy, developmental delay, bone changes, or fractures can be symptoms of vitamin D deficiency.
Vitamin D supplementation can improve muscle strength and reduce fall frequency by approximately 50%.7 Thus, patients who have low bone mineral density or a prior low-impact (fragility) skeletal fracture and those at risk of falling should be evaluated for vitamin D deficiency to reduce the risk of all types of skeletal fractures.
Prevention
Adults less than 65 years of age who do not have year-round effective sun exposure shall consume 600 to 800 international units of vitamin D3 daily to prevent deficiency. Older adults 65 years of age or more shall consume 800 to 1000 international units of vitamin D3 daily to prevent deficiency and to reduce the risk of fractures and falls.
In case of deficiency, recommended doses are much higher.
For adults: Initial supplementation for 8 weeks with Vitamin D3 either 6,000 IU daily or 50,000 IU weekly can be considered.
Children who are vitamin D deficient require 2000 IU/day of vitamin D3 or 50,000 IU of vitamin D3 once weekly for 6 weeks.
By Laboratoires Servier - Smart Servier website: Images related to Fracture of femur (Thigh bone fracture), Bone fractures and Bones -- Download in Powerpoint format.Flickr: Images related to Fracture of femur (Thigh bone fracture), Bone fractures and Bones (in French)., CC BY-SA 3.0, https://commons.wikimedia.org/w/index...
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