Paroxysmal Nocturnal Hemoglobinuria
24.5 هزار بار بازدید -
8 سال پیش
-
Thanks to Hassan Jefri from
Thanks to Hassan Jefri from for meticulously recording this video.
This video is all about a rare clonal hematopoetic disorder called paroxysmal nocturnal hemoglobinuria abbreviated as PNH. PNH is because of the mutation in PIG A gene which codes for GPI (glycophosphotidylinositol). GPI is needed for anchoring DAF and CD59 on red cell membrane. In the absence of DAF and CD59 the red cells will be hemolysed by the compliment system. Complimented mediated hemolysis in paroxysmal nocturnal hemoglobinuria, PNH, leads to complement mediated intravascular hemolysis giving rise to hemoglobinuria, jaundice and anemia. PNH is diagnosed using sucrose hemolysis test or sugar water test, Hams test and flow cytometry.
Watch my video on glycophosphatidylinositol (GPI) as in the link below
Glycophosphatidylinositol (GPI) - A Q...
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This video is all about a rare clonal hematopoetic disorder called paroxysmal nocturnal hemoglobinuria abbreviated as PNH. PNH is because of the mutation in PIG A gene which codes for GPI (glycophosphotidylinositol). GPI is needed for anchoring DAF and CD59 on red cell membrane. In the absence of DAF and CD59 the red cells will be hemolysed by the compliment system. Complimented mediated hemolysis in paroxysmal nocturnal hemoglobinuria, PNH, leads to complement mediated intravascular hemolysis giving rise to hemoglobinuria, jaundice and anemia. PNH is diagnosed using sucrose hemolysis test or sugar water test, Hams test and flow cytometry.
Watch my video on glycophosphatidylinositol (GPI) as in the link below
Glycophosphatidylinositol (GPI) - A Q...
You Can Subscribe to my Channel for REGULAR UPDATES by clicking on SUBSCRIBE button above!
You can follow me on my BLOG by clicking the link below
http://drmungli.blogspot.com/
You can follow my Facebook page Biochemistry Made Easy by Dr Prakash Mungli, MD by clicking the link below. Here I post USMLE step-1 style MCQs and you can participate in discussion.
Facebook: drmungli
8 سال پیش
در تاریخ 1395/11/28 منتشر شده
است.
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