AIRRC6 - Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design (J. Meiler)
333 بار بازدید -
2 سال پیش
-
Biomedical Science Session - May
Biomedical Science Session - May 19th, 2022
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design
Jens Meiler. Professor. Vanderbilt University (USA) and Leipzig University (Germany)
Introduction by Christian Busse (German Cancer Research Center (DKFZ))
Structure-based antibody and antigen design has advanced greatly in recent years, due not only to the increasing availability of experimentally determined structures but also to improved computational methods for both prediction and design. Constant improvements in performance within the Rosetta software suite for biomolecular modeling have given rise to a greater breadth of structure prediction, including docking and design application cases for antibody and antigen modeling. Here, we present an overview of current protocols for antibody and antigen modeling using Rosetta and exemplify those by spciifc applications.
AIRR Community Meeting VI “Exploring New Frontiers”. La Jolla, CA. May 17-19, 2022.
https://www.antibodysociety.org/the-a...
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design
Jens Meiler. Professor. Vanderbilt University (USA) and Leipzig University (Germany)
Introduction by Christian Busse (German Cancer Research Center (DKFZ))
Structure-based antibody and antigen design has advanced greatly in recent years, due not only to the increasing availability of experimentally determined structures but also to improved computational methods for both prediction and design. Constant improvements in performance within the Rosetta software suite for biomolecular modeling have given rise to a greater breadth of structure prediction, including docking and design application cases for antibody and antigen modeling. Here, we present an overview of current protocols for antibody and antigen modeling using Rosetta and exemplify those by spciifc applications.
AIRR Community Meeting VI “Exploring New Frontiers”. La Jolla, CA. May 17-19, 2022.
https://www.antibodysociety.org/the-a...
2 سال پیش
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