Hormones During Puberty With Klinefelter Syndrome
5.6 هزار بار بازدید -
2 سال پیش
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Hi, everyone. I'm Dr. Shanlee
Hi, everyone. I'm Dr. Shanlee Davis. I'm a pediatric endocrinologist that works at the Children's Hospital, Colorado, and the University of Colorado Anschutz Medical Campus. Here we have the Extraordinary Kids Clinic, a specialty clinic for children with XXY and other X and Y variations. I will review some of the most common questions as a pediatric endocrinologist. I take care of many boys with Klinefelter Syndrome.
So the first question is: What hormones do you need to measure? When do you need to measure them?
Hypothalamic pituitary gonadal access is a big long word that we often refer to as HPG access isn't even active until true puberty starts. The brain sends signals to the testes to tell them to make testosterone. This is when the start of puberty is initiated. This can happen anywhere from age 9 to 14 in typically developing boys. And we see the exact onset of puberty in Klinefelter syndrome. However, as puberty progresses in Klinefelter syndrome, the testes can't keep up with the demand for making testosterone in the rest of the body. And so the brain starts sending out signals louder and louder.
Those signals are called Gonadotropin for LH and FSH, and we can measure these hormones in the blood. So once puberty starts, the doctors should begin to evaluate the exam, how the body changes over time, and what these labs look like in the blood. So LH FSH and total testosterone. The relationship between those labs makes a difference when deciding when and how to consider starting testosterone replacement in boys with Klinefelter Syndrome.
Disclaimer:
The Video Content has been made available for informational and educational purposes only. Living With XXY does not make any representation or warranties concerning the video content's accuracy, applicability, fitness, or completeness.
The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen on YouTube.
Living With XXY at this moment disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties.
To learn more information about Klinefelter syndrome 47 XXY, please visit https://livingwithxxy.org/
So the first question is: What hormones do you need to measure? When do you need to measure them?
Hypothalamic pituitary gonadal access is a big long word that we often refer to as HPG access isn't even active until true puberty starts. The brain sends signals to the testes to tell them to make testosterone. This is when the start of puberty is initiated. This can happen anywhere from age 9 to 14 in typically developing boys. And we see the exact onset of puberty in Klinefelter syndrome. However, as puberty progresses in Klinefelter syndrome, the testes can't keep up with the demand for making testosterone in the rest of the body. And so the brain starts sending out signals louder and louder.
Those signals are called Gonadotropin for LH and FSH, and we can measure these hormones in the blood. So once puberty starts, the doctors should begin to evaluate the exam, how the body changes over time, and what these labs look like in the blood. So LH FSH and total testosterone. The relationship between those labs makes a difference when deciding when and how to consider starting testosterone replacement in boys with Klinefelter Syndrome.
Disclaimer:
The Video Content has been made available for informational and educational purposes only. Living With XXY does not make any representation or warranties concerning the video content's accuracy, applicability, fitness, or completeness.
The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen on YouTube.
Living With XXY at this moment disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties.
To learn more information about Klinefelter syndrome 47 XXY, please visit https://livingwithxxy.org/
2 سال پیش
در تاریخ 1401/08/12 منتشر شده
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