Analyzing high concentration biologic therapeutic formulations

Developing high-dose biologic drugs for subcutaneous injection often requires high-concentration formulations. It also needs to optimize viscosity, solubility, and stability while overcoming analytical, manufacturing, and administration challenges.

During this webinar, our presenters reflect on a set of surveys and discussions that took place within  BioPhorum Development Group's Formulation workstream, as well as a paper published in the Journal of Pharmaceutical Sciences.

Our speakers 🗣️
- Preeti Desai, Senior Principal Scientist, ‪@BristolMyersSquibb‬
- Patrick Garidel, Head of TIP, ‪@boehringeringelheim‬
- Francisca Gbormittah, Senior Manager, ‪@GSK‬
- Douglas Kamen, Associate Director, ‪@Regeneron‬
- Brittney Mills, Principal Research Scientist, ‪@AbbVie‬
- Chakravarthy Nachu Narasimhan, Senior Principal Scientist, ‪@Merck‬
- Shubhadra Singh, Scientific Leader, ‪@GSK‬
- Elaine S.E. Stokes, lead Facilitator, BioPhorum
- Erika Walsh, Associate Principal Scientist, ‪@Merck‬

Chapters:
0:00 Webinar and BioPhorum introduction
6:09 Solubility
11:00 Viscosity
14:25 Stability
30:40 Sample preparation and analytical testing considerations
33:56 Technology for delivering large volume doses
37:49 Conclusions

#BioPhorum #DevelopmentGroup #therapeutic #biological #biopharma #biopharmaceutics