Cholesterol Synthesis Pathway || Cholesterol Metabolism || Biochemistry

Biochemistry Basics by Dr Amit
Biochemistry Basics by Dr Amit
10.2 هزار بار بازدید - 4 سال پیش - Cholesterol Metabolism - This video
Cholesterol Metabolism - This video is on the Structure of Cholesterol, Cholesterol synthesis, regulation of cholesterol metanolism and metabolic fates cholesterol along with NEET PG MCQs.
1. Cholesterol Structure -2:00 minutes
2. Cholesterol Synthesis-3:18minutes
3. Mechanism of Statins-6:50minutes
4. Energy requirement of Cholesterol Synthesis-8:50minutes
5. Regulation of Cholesterol Synthesis-10:00 minutes
6. Metabolic fates of cholesterol - 13:10 minutes\
7. NEET PG MCQs - 14:27 minutes

Cholesterol is the major sterol in human
Cholesterol is an amphipathic lipid which can be synthesized by most cells of the body and it is obtained from the diet in foods of animal origin.
It is not synthesized in plants.
The major source of dietary cholesterol is egg yolk and meat, particularly liver.
Normal Level Total Cholesterol in Blood is 120-200mg/dl
An abnormality in either cholesterol metabolism or transport through the plasma appears to be related to the development of atherosclerosis that can lead to myocardial infarction or stroke.
Cholesterol is synthesized by most cells of the  body. Liver and intestine are major site of cholesterol synthesis.
All 27-carbon atoms of cholesterol are derived from the    acetyl-CoA.
The reactions of cholesterol biosynthesis occurs into 5  stages
Condensation of three molecules of acetyl-CoA to   mevalonate
2. Conversion of mevalonate to activated isoprene units
3. Polymerization of six isoprene units to form squalene
4. Cyclization of squalene to form parent steroid  
    nucleus lanosterol
5. Formation of cholesterol from lanosterol.
4 سال پیش در تاریخ 1399/02/08 منتشر شده است.
10,202 بـار بازدید شده
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