Drug-Receptor Interactions: Affinity, Efficacy, CRCs & Antagonism
3.9 هزار بار بازدید -
11 ماه پیش
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In this lecture EKG is going to cover drug-receptor interactions.
We’ll explore important concepts like drug binding, affinity, efficacy, potency, and concentration response curves. We’ll also break down the role of agonist drugs and dive into the different types of antagonism.
Feeling a little under the dose of pharmacology? Subscribe to the channel and we'll fill your prescription with more pharma content! Seriously though be an agonist drug and bind to the subscribe button 😉
Lecture Overview:
0:00 Intro
0:22 Concept of Drug-Receptor Interaction
3:50 Affinity, Law of Mass Action & Equilibrium Dissociation Constant (KD)
11:55 Efficacy & Receptor States
16:50 Concentration-Response Curves (CRCs)
21:02 Emax & EC50
23:37 Potency
29:48 Subdivisions within Agonists: Full & Partial
31:22 Types of Antagonism - Competitive (Reversible & Surmountable) & Non-competitive (Irreversible & Insurmountable)
✏️ All diagrams were made by EKG.
For educational purposes only; NOT medical or other advice.
Lecture Source:
Ritter, J., Flower, R.J., Henderson, G., Yoon Kong Loke and Rang, H.P. (2018). Rang and Dale’s Pharmacology. 9th ed. Endinburgh: Elsevier.
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Pharmacodynamics: GPCRs & Second Messengers - G-Protein Coupled Receptors (GPCRs) &...
Introduction To Pharmacokinetics - Introduction to Pharmacokinetics: ADM...
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https://www.seevid.ir/c/EKGScience?...
In this lecture EKG is going to cover drug-receptor interactions.
We’ll explore important concepts like drug binding, affinity, efficacy, potency, and concentration response curves. We’ll also break down the role of agonist drugs and dive into the different types of antagonism.
Feeling a little under the dose of pharmacology? Subscribe to the channel and we'll fill your prescription with more pharma content! Seriously though be an agonist drug and bind to the subscribe button 😉
Lecture Overview:
0:00 Intro
0:22 Concept of Drug-Receptor Interaction
3:50 Affinity, Law of Mass Action & Equilibrium Dissociation Constant (KD)
11:55 Efficacy & Receptor States
16:50 Concentration-Response Curves (CRCs)
21:02 Emax & EC50
23:37 Potency
29:48 Subdivisions within Agonists: Full & Partial
31:22 Types of Antagonism - Competitive (Reversible & Surmountable) & Non-competitive (Irreversible & Insurmountable)
✏️ All diagrams were made by EKG.
For educational purposes only; NOT medical or other advice.
Lecture Source:
Ritter, J., Flower, R.J., Henderson, G., Yoon Kong Loke and Rang, H.P. (2018). Rang and Dale’s Pharmacology. 9th ed. Endinburgh: Elsevier.
---
💙 SUPPORT EKG SCIENCE
PayPal - https://www.paypal.com/paypalme/ekgsc...
📸 SOCIAL MEDIA
Instagram - Instagram: ekgscience
Twitter - Twitter: ekgscience
📚 STUDY NEXT:
Pharmacodynamics: GPCRs & Second Messengers - G-Protein Coupled Receptors (GPCRs) &...
Introduction To Pharmacokinetics - Introduction to Pharmacokinetics: ADM...
🌏 Our mission here at EKG Science is to serve the current and future generations of learners by creating free, world-class science lectures.
Write your story.
Remember, subtract complexity & slow down.
#pharmacodynamics #pharmacology #ekgscience
11 ماه پیش
در تاریخ 1402/06/01 منتشر شده
است.
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