Swelling Index = Determination of Swelling Index of Isabgol | Psyllium Husk |Swelling Index Test

This video is also available in ENGLISH Swelling Index = Determination of Swelling Index of Isabgol (Psyllium Husk) ENGLISH    • Swelling Index | Determination of Swe...   Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - play.google.com/store/apps/details?id=co.bolton.nq… SWELLING INDEX The swelling index is the volume in ml taken up by the swelling of 1gm of plant material under specified conditions. Its determination is based on addition of water or a swelling agent as described in test procedure. The swelling index is used to find the swelling capacity of given crude drugs. When the drug (here Isabgol) is dipped into the water in a measuring cylinder it gets swell after some time by absorbing it. When the Isabgol is mixed or dipped into the specific volume of water then it starts to absorb water and begins to swell. the swelling increases its size and mass, the exact hight till it swells is known as a swelling index. The swelling index depends on the mucilage present in the crude drug or given sample. The swelling index is one of the most important properties for those drugs which claim to be effective as anti-constipation or simply laxative. Isabgoal is used mainly as a bulk laxative to get relieved of constipation. when it is taken at night it absorbs water and swell and increase the movement of stool. so to evaluate the quality of isabgol and to check the presence of any kind of adulteration this swelling index test is performed. This test is basically performed for the evaluation of the presence of adulteration. Adulteration is a practice of substituting the original drug completely or partially with other similar looking substance The substance, which is mixed, is either free from or inferior in quality in terms of chemical and therapeutic properties. Plantago such as P. psyllium, P. arenaria, P. lanceolata etc. contain mucilage in the epidermis of the seeds. Polysaccharides in the mucilage of these seeds constitute a diverse class of biological macromolecules with a broad range of physiochemical properties which are widely used for various applications in Pharmacy and medicine. All these seeds can be evaluated by measuring the volume of mucilage produced within 24 h. It is termed as swelling Factor. It is defined in the B. P. as the volume in milliliter occupied by 1 g of a drug including any adhering mucilage aіer it has swollen in an aqueous liquid for 24 h. The swelling factor reflects the mucilage content of the seeds. The seeds of Plantago ovata mainly contains mucilage which is a polysaccharide (20-30%) consist of highly branched, weakly acidic arabinoxylans (upto 85%) with a xylan backbone and branches of arabinose, xylose and 2-o-(galacturonic acid)-r-rhamnose residues. Get in touch with the solution by just clicking following links- Facebook Group- www.facebook.com/groups/solutionpharamcy Facebook Page- www.facebook.com/pharmavideo/ New channel (Pharmacy Dictionary) -    / @pharmacydictionary   Instagram- www.instagram.com/solutionpharmacy/ E-Mail for official and other work - [email protected] LinkedIn- linkedin.com/in/pushpendrakpatel #solutionpharmacy #Pharmacologyclass #GPATonlinetest

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