Weighing Balance Calibration (@PharmaScholars )

Chapter 41 of the USP standards is titled ‘balances’ and refers to the mandatory requirements for the accurate weighing of materials using a balance.  On 1st December 2013, the new regulations of USP Chapter 41 went into effect and this chapter is mandatory in a Pharmaceutical Quality Control (QC) laboratory, where weighing is a fundamental step in almost every workflow.

The weighing of a sample is typically the first step in an analytical procedure, and therefore has the potential to propagate through the process and cause the inaccuracy of the final result. Therefore, the USP has set official requirements for balances in order to reduce uncertainties within analysis that could be detrimental to human health.

The mandatory Chapter 41 states that a balance should be properly calibrated over the operating range. Repeatability and accuracy requirements are defined, with acceptance limits and permissible test weights. The White Paper ‘Weighing According to US Pharmacopeia’ explains the requirements in more detail.

(‪@PharmaScholars‬ )
#Usp_chapter_41
#USP_Chapter_1251
#Repeatability
#Accuracy
#SENSTIVITY
#eccentricity
#Linearity