2. Anemia Of Chronic Disease | USMLE Step 1 Pathology
2 هزار بار بازدید -
3 ماه پیش
-
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- Instagram: drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Anemia of Chronic Disease
Anemia of Chronic Disease (ACD), also known as anemia of inflammation, is a type of anemia commonly encountered in clinical practice and is essential knowledge for mastering USMLE Step 1 Pathology. This form of anemia arises secondary to chronic inflammatory conditions, such as infections, autoimmune diseases, and malignancies, where pro-inflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) inhibit erythropoiesis and disrupt iron metabolism. The hallmark of ACD is the disruption of iron homeostasis, characterized by impaired iron utilization despite normal or elevated iron stores. 💊 Inflammatory mediators induce hepcidin production by the liver, which reduces iron absorption from the gut and sequesters iron within macrophages, impairing its release for erythropoiesis. Consequently, patients present with normocytic or microcytic anemia with low serum iron, low transferrin saturation, and normal or elevated ferritin levels. Treatment primarily revolves around managing the underlying inflammatory condition, as correction of the anemia typically follows resolution of the underlying disease process. Understanding the pathophysiology and management of ACD is crucial for physicians to provide comprehensive care to patients with chronic inflammatory disorders.
#AnemiaOfChronicDisease #USMLEStep1 #Pathology #MedicalEducation #Inflammation #Erythropoiesis #IronMetabolism #Hepcidin #ProInflammatoryCytokines #MedicalStudents #HealthcareEducation
#fmge #fmgevideos #rapidrevisionfmge #fmgejan2023 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2023 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #anemia
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Anemia of Chronic Disease
Anemia of Chronic Disease (ACD), also known as anemia of inflammation, is a type of anemia commonly encountered in clinical practice and is essential knowledge for mastering USMLE Step 1 Pathology. This form of anemia arises secondary to chronic inflammatory conditions, such as infections, autoimmune diseases, and malignancies, where pro-inflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) inhibit erythropoiesis and disrupt iron metabolism. The hallmark of ACD is the disruption of iron homeostasis, characterized by impaired iron utilization despite normal or elevated iron stores. 💊 Inflammatory mediators induce hepcidin production by the liver, which reduces iron absorption from the gut and sequesters iron within macrophages, impairing its release for erythropoiesis. Consequently, patients present with normocytic or microcytic anemia with low serum iron, low transferrin saturation, and normal or elevated ferritin levels. Treatment primarily revolves around managing the underlying inflammatory condition, as correction of the anemia typically follows resolution of the underlying disease process. Understanding the pathophysiology and management of ACD is crucial for physicians to provide comprehensive care to patients with chronic inflammatory disorders.
#AnemiaOfChronicDisease #USMLEStep1 #Pathology #MedicalEducation #Inflammation #Erythropoiesis #IronMetabolism #Hepcidin #ProInflammatoryCytokines #MedicalStudents #HealthcareEducation
#fmge #fmgevideos #rapidrevisionfmge #fmgejan2023 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2023 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #anemia
3 ماه پیش
در تاریخ 1403/01/31 منتشر شده
است.
2,060
بـار بازدید شده