Is RU-58841 Safe? | What we DO know and what we DON'T...

KwRx
KwRx
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Timestamps:
- 0:14 - 1:17 Introduction
- 1:17 - 2:03 Phase 1 Human Clinical Trial:
- 2:03-2:41 Phase 2 Human Clinical Trial:
- 2:42-4:52 I messaged the company that researched RU-58841: Unknown Results (Exact letter they sent me: 3:33)
- 4:53 Monkey Animal Studies (Stump-tailed Macaques)
-- 5:48 RU-58841 Phase 1 Human Clinical Trial results: Good Efficacy and safety! (90 subjects)
-- 6:43 Dose-dependent and long term effects of RU58841 (androgen receptor blocker) on hair growth in the bald Stump-tailed Macaque.
-- 9:40 Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of Stump-tailed Macaques
-- 11:21 Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal Stump-tailed Macaque
-- 14:56 What we know of Phase 1 Human Clinical Trials: It is well tolerated and has a similar efficacy profile to oral Finasteride.
-- 16:07 Fake RU-58841 online, unreliable nature of experimental chemicals.

Links for you
Dose-dependent and long term effects of RU58841 (androgen receptor blocker) on hair growth in the bald stumptailed Macaque.
https://www.infona.pl/resource/bwmeta...

Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal stumptailed macaque
https://pubmed.ncbi.nlm.nih.gov/8977424/

Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques
https://pubmed.ncbi.nlm.nih.gov/97987...

Phase 1 PSK-3841 (RU-58841) Clinical Trial:
A double blind, randomised, vehicle-controlled, safety and tolerance study of topical PSK 3841 solution at 5% administered twice daily over four weeks to healthy Caucasian males with androgenetic alopecia
https://www.isrctn.com/ISRCTN49873657

Phase 2 PSK-3841 (RU-58841) Clinical Trial:
A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%)
https://www.isrctn.com/ISRCTN71083772

Topical anti-androgen PSK-3841 (RU-58841)
https://web.archive.org/web/200611212...

RU-58841 stats
https://drugs.ncats.io/substance/0D8F...
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