Kendrew Lecture 2021 pt2 - Highly accurate protein structure prediction with AlphaFold - John Jumper
14.9 هزار بار بازدید -
3 سال پیش
-
MRC Laboratory of Molecular Biology
MRC Laboratory of Molecular Biology John Kendrew Lecture 2021 part 2
Highly accurate protein structure prediction with AlphaFold
Speaker: John Jumper, AlphaFold lead, DeepMind.
Abstract:
Predicting a protein’s structure from its primary sequence has been a grand challenge in biology for the past 50 years, holding the promise to bridge the gap between the pace of genomics discovery and resulting structural characterization. In this talk, we will describe work at DeepMind to develop AlphaFold, a new deep learning-based system for structure prediction that achieves high accuracy across a wide range of targets. We demonstrated our system in the 14th biennial Critical Assessment of Protein Structure Prediction (CASP14) across a wide range of difficult targets, where the assessors judged our predictions to be at an accuracy “competitive with experiment” for approximately 2/3rds of proteins. The talk will cover both the underlying machine learning ideas and the implications for biological research.
Read more about the lecture and David's work here: https://www2.mrc-lmb.cam.ac.uk/john-k...
-
About the MRC Laboratory of Molecular Biology (LMB):
The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health.
More links:
Official Site: https://www2.mrc-lmb.cam.ac.uk/
Facebook: Facebook: MRC.LMB
Twitter: Twitter: MRC_LMB
Instagram: Instagram: mrc_lmb
LinkedIn: LinkedIn: mrc-laboratory-of-molecular-biology
Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: https://www.youtube.com/user/LMBCambr...
Highly accurate protein structure prediction with AlphaFold
Speaker: John Jumper, AlphaFold lead, DeepMind.
Abstract:
Predicting a protein’s structure from its primary sequence has been a grand challenge in biology for the past 50 years, holding the promise to bridge the gap between the pace of genomics discovery and resulting structural characterization. In this talk, we will describe work at DeepMind to develop AlphaFold, a new deep learning-based system for structure prediction that achieves high accuracy across a wide range of targets. We demonstrated our system in the 14th biennial Critical Assessment of Protein Structure Prediction (CASP14) across a wide range of difficult targets, where the assessors judged our predictions to be at an accuracy “competitive with experiment” for approximately 2/3rds of proteins. The talk will cover both the underlying machine learning ideas and the implications for biological research.
Read more about the lecture and David's work here: https://www2.mrc-lmb.cam.ac.uk/john-k...
-
About the MRC Laboratory of Molecular Biology (LMB):
The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health.
More links:
Official Site: https://www2.mrc-lmb.cam.ac.uk/
Facebook: Facebook: MRC.LMB
Twitter: Twitter: MRC_LMB
Instagram: Instagram: mrc_lmb
LinkedIn: LinkedIn: mrc-laboratory-of-molecular-biology
Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: https://www.youtube.com/user/LMBCambr...
3 سال پیش
در تاریخ 1400/07/28 منتشر شده
است.
14,937
بـار بازدید شده