The role of PRAME immunohistochemistry in the diagnostic approach to melanocytic lesions

As a regional leader in advanced and integrated solutions in pathology and diagnostic testing, Roche Diagnostics Australia joined the XXXIV International Congress of the International Academy of Pathology as a platinum sponsor.

Contributing to the scientific program of the event held in Sydney in October 2022, Roche sponsored a symposium by Dr Robert Rawson, an Australian pathologist associated with the Melanoma Institute Australia and Royal Prince Alfred Hospital.

This is a recording of his presentation on PRAME, a tumour-associated antigen identified by an autologous T-cell epitope in a patient with metastatic cutaneous melanoma.

In his presentation, Dr. Robert Rawson discusses the history and context of PRAME immunohistochemistry, the role in the assessment of cutaneous melanocytic lesions, and other roles of PRAME, including nodal deposits, margin assessment, assessment of melanocytic lesions at other sites, and using PRAME in undifferentiated malignancies.

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• #science_technology
• #melanoma
• #prame
• #immunohistochemistry
• #pathology