How OPZELURA™ (ruxolitinib) cream 1.5% Works with Dr. Rocco Serrao

Read below for Selected Safety Information.

A big part of feeling confident in your eczema treatment is understanding the way it works in your body. Watch dermatologist Dr. Rocco Serrao explain how OPZELURA is thought to work to provide relief from mild to moderate eczema that you can see and feel.

Please see the Full Prescribing Information, including Boxed Warning, and Medication Guide for OPZELURA.

Prescribing Information: https://www.opzelura.com/prescribing-...

Medication Guide: https://www.opzelura.com/medication-g...

This video is intended for informational use only, and is not designed to replace the medical advice of your Healthcare Professional. OPZELURA is a prescription medicine used on the skin (topical) for the short-term and non-continuous chronic treatment of mild to moderate eczema (atopic dermatitis) in non-immunocompromised adults and children 12 years of age and older whose disease is not well controlled with topical prescription therapies or when those therapies are not recommended. The use of OPZELURA along with therapeutic biologics, other JAK inhibitors, or strong immunosuppressants such as azathioprine or cyclosporine is not recommended. It is not known if OPZELURA is safe and effective in children less than 12 years of age with atopic dermatitis or nonsegmental vitiligo.

Selected Safety Information

OPZELURA can cause serious side effects including serious infections, increased risk of death due to any reason, cancer and immune system problems, increased risk of major cardiovascular events, and blood clots.

OPZELURA can lower your ability to fight infections, including TB or hepatitis B or C. Serious lung infections, skin cancer, blood clots, and low blood cell counts occurred with OPZELURA. Before starting OPZELURA, tell your doctor if you have an infection, are being treated for one, have TB or have been in close contact with someone with TB; have or had hepatitis B or C. Your doctor should check for infections before and during treatment. Tell your doctor if you had blood clots in your legs or lungs. OPZELURA may cause low platelet, low red and white blood cell counts.

In people taking JAK inhibitors, serious infections, increased risk of death, lymphoma, other cancers, and major cardiovascular events have occurred. OPZELURA is a topical JAK inhibitor. People 50 and older with at least 1 heart disease risk factor have an increased risk of heart attack, stroke, blood clots, and death when taking JAK inhibitors by mouth. The most common side effects seen with OPZELURA were acne and itching where applied.

Call your doctor for medical advice about side effects. To learn more about these and other risks, please read the Important Safety Information at https://www.opzelura.com/.

Please see the Full Prescribing Information and Medication Guide at https://www.opzelura.com/prescribing-... which includes a more complete discussion of the risks associated with OPZELURA.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also report side effects to Incyte Medical Information at 1-855-463-3463.

Sponsored by Incyte Corporation. OPZELURA is a trademark of Incyte.

© 2022, Incyte Corporation.  MAT-OPZ-01229  11/22