Drugs Metabolism || Pharmacokinetics #metabolism #pharmacokinetics @alisclasses9000

This video is all about the Pharmacokinetics Metabolism

1. BioTransformation
    a. Phase 1
         I) Oxidation
         II) Reduction
         III) Hydrolysis
         IV) Cyclization
         V) Decyclization
    b. Phase 2
         I) Glucuronide conjugation
         II) Glycine Conjugation
         III) Glutathione
         IV) Sulfate
         V) Acetylation
        VI) Methylation  
2. Enzymes
    a. Microsomal Enzymes
       I) Induction
       II) Inhibition
    b. Non- Microsomal Enzymes
3. Cytochrome P450
    a. CYP1A1/2
    b. CYP 3A 4/5
    c. CYP 2B6
    d. CYP 2C9
    e. CYP 2C19
    f. CYP 2D6
    g. CYP 2E1
4. Fate of Metabolism



In the next video, I'll discuss Pharmacokinetics Excretion
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