Bente Klarlund - Exercise as Medicine and the role of myokines: a translational perspective
2.5 هزار بار بازدید -
3 سال پیش
-
GUEST LECTUREBente Klarlund - Exercise
GUEST LECTURE
Bente Klarlund - Exercise as Medicine and the role of myokines: a translational perspective
ABSTRACT
Physical activity decreases the risk of a network of diseases, and exercise may be prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia, cardiovascular diseases, and cancer. During the past couple of decades, it has been apparent that skeletal muscle works as an endocrine organ, which can produce and secrete hundreds of myokines that exert their effects in either autocrine, paracrine, or endocrine manners. Recent advances show that skeletal muscle produces myokines in response to exercise, which allow for crosstalk between the muscle and other organs, including brain, adipose tissue, bone, liver, gut, pancreas, vascular bed, and skin, as well as communication within the muscle itself. Although only few myokines have been allocated to a specific function in humans, it has been identified that the biological roles of myokines include effects on, for example, cognition, lipid and glucose metabolism, browning of white fat, bone formation, endothelial cell function, hypertrophy, skin structure, and tumor growth. This suggests that myokines may be useful biomarkers for monitoring exercise prescription for people with, for example, cancer, diabetes, or neurodegenerative diseases.
ABOUT BENTE KLARLUND
Clinical Professor of Integrative Medicine at the Department of Clinical Medicine, University of Copenhagen and Adjunct Professor at the University of Southern Denmark and member of the DIAS Advisory Board.
Furthermore, she is Chief Physician and Centre Director of the Centre for Physical Activity Research (CFAS) at Rigshospitalet.
Due to her background and award-winning research, she is one of the most frequently used researchers in the media within topics on health, diet, exercise and Danes’ health. She has written several books on the subject and is the author of more than 600 scientific articles, just as she is often used as a lecturer in both Denmark and at international conferences.
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Danish Institute for Advanced Study (D-IAS) is a national elite center at University of Southern Denmark (SDU) that sets the framework for excellent research.
We offer an extensive program of different prestigious lectures and we aim to inspire groundbreaking ideas through the meeting of minds within all disciplines.
D-IAS include chairs from all five faculties at SDU and three external chairs from the University of Copenhagen. The most important core in D-IAS we believe is our team of 16 very promising D-IAS Assistant Professors.
https://danish-ias.dk/
Bente Klarlund - Exercise as Medicine and the role of myokines: a translational perspective
ABSTRACT
Physical activity decreases the risk of a network of diseases, and exercise may be prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia, cardiovascular diseases, and cancer. During the past couple of decades, it has been apparent that skeletal muscle works as an endocrine organ, which can produce and secrete hundreds of myokines that exert their effects in either autocrine, paracrine, or endocrine manners. Recent advances show that skeletal muscle produces myokines in response to exercise, which allow for crosstalk between the muscle and other organs, including brain, adipose tissue, bone, liver, gut, pancreas, vascular bed, and skin, as well as communication within the muscle itself. Although only few myokines have been allocated to a specific function in humans, it has been identified that the biological roles of myokines include effects on, for example, cognition, lipid and glucose metabolism, browning of white fat, bone formation, endothelial cell function, hypertrophy, skin structure, and tumor growth. This suggests that myokines may be useful biomarkers for monitoring exercise prescription for people with, for example, cancer, diabetes, or neurodegenerative diseases.
ABOUT BENTE KLARLUND
Clinical Professor of Integrative Medicine at the Department of Clinical Medicine, University of Copenhagen and Adjunct Professor at the University of Southern Denmark and member of the DIAS Advisory Board.
Furthermore, she is Chief Physician and Centre Director of the Centre for Physical Activity Research (CFAS) at Rigshospitalet.
Due to her background and award-winning research, she is one of the most frequently used researchers in the media within topics on health, diet, exercise and Danes’ health. She has written several books on the subject and is the author of more than 600 scientific articles, just as she is often used as a lecturer in both Denmark and at international conferences.
**********
--
Danish Institute for Advanced Study (D-IAS) is a national elite center at University of Southern Denmark (SDU) that sets the framework for excellent research.
We offer an extensive program of different prestigious lectures and we aim to inspire groundbreaking ideas through the meeting of minds within all disciplines.
D-IAS include chairs from all five faculties at SDU and three external chairs from the University of Copenhagen. The most important core in D-IAS we believe is our team of 16 very promising D-IAS Assistant Professors.
https://danish-ias.dk/
3 سال پیش
در تاریخ 1401/01/01 منتشر شده
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