Generation of Action Potential | How Action Potential is Generated in neurons, muscles etc?
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3 سال پیش
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Video Summary:
Resting membrane potential is inside negative. The stimulus that brings the voltage to the threshold produces an action potential. Here, the influx of Na by voltage-gated Na channel produces depolarization. Then Na channels close and K channels open. The exit of K causes repolarization of the membrane. The altered concentration gradients of Na and K are reestablished by the Na-K ATPase pump. Voltage-gated Na channels have an activation gate and an inactivation gate. Opening of activation gate during depolarization allows passage of Na. Then closing inactivation gates stops the Na entry contributing to repolarization. The channel returns to its initial state after resting membrane potential is reestablished. Change in a concentration gradient of Na and K for a single action potential is very very small and millions of action potentials can be passed before the gradient reduces to a significant level. Duration and shape of the action potential can vary in different cells. And finally, generation of action potential involves a positive feedback loop which is rare in the body.
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• Transport Through The Cell Membrane: 11. Transport Through the Cell Membrane
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Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
🌐 Explore our entire animation video library at: https://www.nonstopneuron.com/
Video Summary:
Resting membrane potential is inside negative. The stimulus that brings the voltage to the threshold produces an action potential. Here, the influx of Na by voltage-gated Na channel produces depolarization. Then Na channels close and K channels open. The exit of K causes repolarization of the membrane. The altered concentration gradients of Na and K are reestablished by the Na-K ATPase pump. Voltage-gated Na channels have an activation gate and an inactivation gate. Opening of activation gate during depolarization allows passage of Na. Then closing inactivation gates stops the Na entry contributing to repolarization. The channel returns to its initial state after resting membrane potential is reestablished. Change in a concentration gradient of Na and K for a single action potential is very very small and millions of action potentials can be passed before the gradient reduces to a significant level. Duration and shape of the action potential can vary in different cells. And finally, generation of action potential involves a positive feedback loop which is rare in the body.
🎞 More videos on membrane physiology:
• Transport Proteins: Transport Proteins: Pumps, Channels, ...
• Primary vs Secondary Active Transport: Primary Active Transport vs Secondary...
• Transport Through The Cell Membrane: 11. Transport Through the Cell Membrane
• Na-K-ATPase Pump: NONSTOP Motor: Sodium Potassium ATPas...
• Transport Across Epithelium: Transport Across Epithelium
• Origin of Resting Membrane Potential: Resting Membrane Potential || How Res...
● Follow me at:
• Facebook: Facebook: NonstopNeuron
• Instagram: Instagram: NonstopNeuron
Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
3 سال پیش
در تاریخ 1400/05/25 منتشر شده
است.
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