Introduction to Extraction of Crude Drug | Basics of Extraction | Basics of Phytochemistry (Part 01)

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Introduction to Extraction
Extraction, as the term is used pharmaceutically, involves the separation of medicinally active portions of plant or animal tissues from the inactive or inert components by using selective solvents in standard extraction procedures. The products so obtained from plants are relatively impure liquids, semisolids or powders intended only for oral or external use.

These include classes of preparations known as decoctions, infusions, fluid extracts, tinctures, pilular (semisolid) extracts, and powdered extracts. Such preparations popularly have been called galenicals, named after Galen, the second-century Greek physician. The purposes of standardized extraction procedures for crude drugs are to attain the therapeutically desired portion and to eliminate the inert material by treatment with a selective solvent known as the menstruum. The extract thus obtained may be ready for use as a medicinal agent in the form of tinctures and fluid extracts, it may be further processed to be incorporated in any dosage form such as tablets or capsules, or it may be fractionated to isolate individual chemical entities such as ajmalicine, hyoscine, and vincristine, which are modern drugs. Thus, standardization of extraction procedures contributes significantly to the final quality of the herbal drug.

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