Synthesis of Halothane - Medicinal chemistry
1.1 هزار بار بازدید -
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Halothane, 2-bromo-2-chloro-1,1,1-trifluorethane (1.1.2), is made
Halothane, 2-bromo-2-chloro-1,1,1-trifluorethane (1.1.2), is made by the addition of hydrogen fluoride to tricholoroethylene and simultaneous substitution of chlorine atoms in the presence of antimony(III) chloride at 130 °C. The resulting 2-chloro-1,1,1-trifluorethane (1.1.1) undergoes further bromination at 450 °C to form halothane [1–3].
2 سال پیش
در تاریخ 1401/02/12 منتشر شده
است.
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