5 Biochemistry major | Biology | Glucose uptake | insulin and non insulin mediated

68 بار بازدید - 4 سال پیش - How do carbohydrate affect our
How do carbohydrate affect our health and what is the secrets of carbohydrates and if the carbohydrates is affect our body ,so we we need the carbohydrate in our meals?
كيف تؤثر الكربوهيدرات على صحتنا وما هي أسرار الكربوهيدرات وإذا كانت الكربوهيدرات تؤثر على أجسامنا ، لذلك نحن بحاجة إلى الكربوهيدرات في وجباتنا؟
Insulin mediates glucose uptake into adipose tissue and skeletal muscle through GLUT4 glucose transporters. ... Insulin acts by increasing the glucose transport rate of each transporter, by increasing the number of functional glucose transporters, or by a combination of both mechanisms.

Physical exercise induces a rapid increase in the rate of glucose uptake in the contracting skeletal muscles. The enhanced membrane glucose transport capacity is caused by a recruitment of glucose transporters (GLUT4) to the sarcolemma and t-tubules.

insulin
Like many hormones, insulin exerts its actions through binding to specific receptors present on many cells of the body, including fat, liver, and muscle cells. The primary action of insulin is to stimulate glucose disappearance.

Glucagon is a glucoregulatory peptide hormone that counteracts the actions of insulin by stimulating hepatic glucose production and thereby increases blood glucose levels.

As insulin is not required for GLUT1- or GLUT3-mediated glucose transport, insulin is not needed for glucose transport into most brain cells. ... During the past decade, acute insulin action in the CNS has been reported to regulate whole-body metabolic function.

It should be noted here that there are some tissues that do not require insulin for efficient uptake of glucose: important examples are brain and the liver. This is because these cells don't use GLUT4 for importing glucose, but rather, another transporter that is not insulin-dependent. biology biochemistry major
4 سال پیش در تاریخ 1399/05/08 منتشر شده است.
68 بـار بازدید شده
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