SSRIs Prevent the Progression of COVID-19

Can a drug typically used to treat depression help prevent the progression of COVID-19? This week we discuss a clinical study that explores just that. Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/33180097/ The Effects of Serotonin in Immune Cells 10.3389/fcvm.2017.00048 Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/33180097/ Fluoxetine (a.k.a. Prozac) is effective as an anti-viral, study suggests https://www.sciencedaily.com/releases/2012/07/120727171919.htm Immunomodulatory Effects Mediated by Serotonin https://www.hindawi.com/journals/jir/2015/354957/ Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells https://www.nature.com/articles/s41598-018-20173-y.pdf?origin=ppub The possible immunoregulatory and anti-inflammatory effects of selective serotonin reuptake inhibitors in coronavirus disease patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382922/

• #science_technology
• #covid_19
• #coagulation
• #serotonin
• #ssri
• #fluvoxamine
• #fluoxetine
• #immunology
• #immunological
• #placebo
• #clinical
• #sert
• #serotonin_reuptake_inhibitor
• #reuptake
• #cytokines
• #prozac
• #immune_cells
• #depression
• #5_ht
• #symptoms
• #drugs_that_work_against_coronavirus
• #drugs_to_treat_covid19
• #therapies_for_covid19
• #anti_covid_drugs
• #covid_clinical_trials