Making and Testing The ANTI-SPICY Molecule (Capsazepine)

Chemiolis
Chemiolis
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In this video I am making and self-testing the molecule Capsazepine (albeit crude), a molecule that blocks access to the receptor activated by the spicy-molecule capsaicin, thus removing its ability to cause you the spicy feeling. There is no known literature on its use on humans, it is used to study the TRPV1 ion-channel (spicy/heat receptor) but only in biology or biochemistry.

For the azepine: https://onlinelibrary.wiley.com/doi/1...
For the isothiocyanate I used a general procedure from: https://scihub.se/https://doi.org/10....
For the final coupling: https://sci-hub.se/https://doi.org/10...

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Check out  @LabCoatz_Science  who notified me of this molecule.

This video is sponsored by Curiosity Stream.
8 ماه پیش در تاریخ 1402/09/24 منتشر شده است.
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