Regulation of Aldosterone Secretion

In this video, we discuss how ANGII, High Extracellular Potassium levels, and ACTH affect aldosterone synthesis and secretion. We also talk about two negative feedback cycles that affect renin release and, therefore, aldosterone secretion.
DISCLAIMER: These videos are NOT meant to replace your lecture attendance, taking lecture notes, and reading the assigned readings in your textbook. These videos are only intended to aid you in understanding the material. Since our understanding of physiology is constantly updating, please use your professor's lectures and/or your textbook as your primary sources of information since these are more likely to be up to date. Thank you!
Sources Used:
Textbook: Boron and Boulpaep "MEDICAL PHYSIOLOGY", 3rd Edition, Chapter Title: "CHAPTER 50: The Adrenal Gland", Section Titles Used: "Angiotensin II, K, and ACTH all stimulate aldosterone secretion", and "Aldosterone exerts indirect negative feedback on the renin-angiotensin axis by increasing effective circulating volume and by lowering plasma [K]", Chapter Author: Eugene J. Barrett, pages used: pgs. 1027-1030.
Research Paper: Nogueira EF, Bollag WB, Rainey WE. Angiotensin II regulation of adrenocortical gene transcription. Mol Cell Endocrinol. 2009, April 29;302(2):230-6. doi:10.1016/j.mce.2008.08.024. Epub 2008 Sep 3. PMID:18812209; PMCID: PMC3752678.
Songs Used:
Intro and Outro: "Wrong" by Dan Henig
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