3- Medicinal Chemistry of ANTIBIOTICS : Penicillin -Cephalosporins -Monobactam - Carbapenem شرح عربي
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- Classes of Antibiotics
1- B-Lactam antibiotics: A- Penicillins
- Nomenclature of penicillins
- Essential structure features of penicillins
- Stability of Benzylpenicillin:
A. Nucleophilic attack (by OH-)
B. Electrophilic attack (by gastric acidity)
C. Penicillins sensitive to B-lactamases
- Classification of Penicillins : Natural - Semi-synthetic
- Acid stable semisynthetic penicillins (ORAL)
B-Lactamase stable penicillins
C. Broad spectrum penicillins
- B-Lactamase Inhibitors: Sulbactam / Clavulanic
- Mechanism of action and assay of penicillins
- Cephalosporins
- The structure of cephalosporin C
- SAR of Cephalosporins
- Classification of Cephalosporins
B- Non-Classical B-Lactam antibiotics
Monobactams / Carbapenem
Penicillin vs. Superbugs: How Medicinal Chemistry Fights Back with Antibiotics
Beyond Penicillin: Exploring the Diverse World of Beta-Lactam Antibiotics
From Mold to Medicine: A Look at the Medicinal Chemistry of Penicillins, Cephalosporins, Monobactams & Carbapenems
Can Bacteria Be Outwitted? Unveiling the Power of Medicinal Chemistry in Antibiotics
The Antibiotic Arsenal: Penicillins, Cephalosporins & More Explained!
Evolution of a Lifesaver: How Medicinal Chemistry Improved Penicillin and Beyond
Beta-Lactam Antibiotics: A Deep Dive into Penicillins, Cephalosporins, Monobactams & Carbapenems
Structure-Activity Relationships: Optimizing Beta-Lactam Antibiotics
The Penicillin Legacy: How Medicinal Chemistry Gave Rise to New Antibiotic Classes
PDF LINK:
https://drive.google.com/drive/folder...
- Classes of Antibiotics
1- B-Lactam antibiotics: A- Penicillins
- Nomenclature of penicillins
- Essential structure features of penicillins
- Stability of Benzylpenicillin:
A. Nucleophilic attack (by OH-)
B. Electrophilic attack (by gastric acidity)
C. Penicillins sensitive to B-lactamases
- Classification of Penicillins : Natural - Semi-synthetic
- Acid stable semisynthetic penicillins (ORAL)
B-Lactamase stable penicillins
C. Broad spectrum penicillins
- B-Lactamase Inhibitors: Sulbactam / Clavulanic
- Mechanism of action and assay of penicillins
- Cephalosporins
- The structure of cephalosporin C
- SAR of Cephalosporins
- Classification of Cephalosporins
B- Non-Classical B-Lactam antibiotics
Monobactams / Carbapenem
Penicillin vs. Superbugs: How Medicinal Chemistry Fights Back with Antibiotics
Beyond Penicillin: Exploring the Diverse World of Beta-Lactam Antibiotics
From Mold to Medicine: A Look at the Medicinal Chemistry of Penicillins, Cephalosporins, Monobactams & Carbapenems
Can Bacteria Be Outwitted? Unveiling the Power of Medicinal Chemistry in Antibiotics
The Antibiotic Arsenal: Penicillins, Cephalosporins & More Explained!
Evolution of a Lifesaver: How Medicinal Chemistry Improved Penicillin and Beyond
Beta-Lactam Antibiotics: A Deep Dive into Penicillins, Cephalosporins, Monobactams & Carbapenems
Structure-Activity Relationships: Optimizing Beta-Lactam Antibiotics
The Penicillin Legacy: How Medicinal Chemistry Gave Rise to New Antibiotic Classes
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