Modeling the human brain using induced pluripotent stem cells iPSCs

Presented By:
Anjana Nityanandam, Ph.D

Speaker Biography:
Dr. Anjana Nityanandam is a developmental neurobiologist with expertise in human induced pluripotent stem cells (iPSCs). She completed her PhD in developmental neuroscience with Prof. Victor Tarabykin at The Max Planck institute for Experimental Medicine in Goettingen, Germany. She then moved to the Baldwin Lab at The Scripps Research Institute in La Jolla, CA, for postdoctoral research. Here Dr. Nityanandam trained in reprogramming, handling and differentiating human iPSCs. Her experience in neurodevelopment and training in the rapidly progressing field of iPSC technology led her to St. Jude Children's Research Hospital in Memphis, TN, five years ago. She was hired to build and establish a stem cell-based disease modeling lab with an emphasis on research and innovation and with the goal of supporting PI's interested in creating and studying disease models using human iPSCs.

Webinar:
Modeling the human brain using induced pluripotent stem cells (iPSCs)

Webinar Abstract:
The goal of this educational webinar is to introduce the audience to induced pluripotent stem cells (iPSCs) and the ways in which they are being used to advance basic and applied medical research. Dr. Nityanandam will talk about ways to generate and characterize iPSCs, and show examples of their successful application towards addressing biological questions. She will specifically focus on how her lab is trying to use iPSCs to recreate different regions of the human brain in a physiologically relevant three-dimensional format. And how they have applied these brain models to understand disease biology. Dr. Nityanandam will also delve into the challenges in the field and the quality control measures that seem necessary to improve reliability and reproducibility of data.

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