How to study learning and memory in mammals - plasticity and imaging of the living brain

In this episode, we talk to Prof. Anthony Holtmaat, a leading researcher in the field of learning and memory from Geneva University Neurocenter. Join us as we explore the substrates of learning and memory, imaging techniques such as two-photon microscopy, synapses, the importance of the thalamus, and even the possibility of inserting false memories. Tune in to this enlightening episode and gain fresh perspectives on the inner workings of our remarkable brains! 🧠🎙️

Our channel is supported by International Max Planck Research School (IMPRS) for Neurosciences, the European Neuroscience Institute, as well as Cluster of Excellence Multiscale Bioimaging (MBExC) in Göttingen, Germany. The views presented on this channel are not representative of IMPRS or MBExC.

#Neuroscience #memory #learning #microscopy #science #sciencepodcast #brain
#göttingen #IMPRS #MBExC #AcademicChatter #SciComm #PhD #imaging #OpenScience #OpenAccess

Timestamps:
00:00:00 Intro
00:02:37 Research of Prof. Holtmaat: substrate of learning and memory
00:03:46 What is learning and memory?
00:10:31 Do we want to understand only how the human brain works?
00:12:35 Imaging techniques and tools for studying learning and memory
00:17:06 Two-photon calcium imaging
00:24:10 Combining Two-photon microscopy with genetically encoded calcium indicators (GECIs)
00:28:38 Imaging from the cranial window in animals
00:33:30 What are synapses?
00:38:10 Prof. Holtmaat’s work on protein lifetimes
00:47:00 Why are there an enormous number of synapses in the cerebellum?
00:49:50 Using whiskers for studying learning
00:55:10 What is so important about the thalamus?
01:00:59 Is it possible to insert false memories?
01:11:21 Neuronal changes in disrupted memory

References:
https://www.nature.com/articles/s4358...
https://www.ncbi.nlm.nih.gov/pmc/arti...
https://pubmed.ncbi.nlm.nih.gov/36202...
https://cellways.blogspot.com/2012/02/
https://cpb.iphy.ac.cn/article/2015/c...

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Neuroscience and Beyond team:
Svilen Georgiev
Kristina Jevdokimenko
Ahsen Konaç Sayıcı
Beatriz Apgaua
Mels Akhmetali

#neuroscience #brain #science #podcast #göttingen #IMPRS #MBExC
#AcademicChatter #SciComm #PhD #microscopy #imaging #OpenScience #OpenAccess