Determining percent purity using Quantitative Proton NMR (qHNMR/qNMR)
13.3 هزار بار بازدید -
6 سال پیش
-
qNMR (quantitative NMR) or qHNMR
qNMR (quantitative NMR) or qHNMR (quantitative proton NMR) can be used as a purity assay to assess the percent purity of an NMR sample.
This video provides an overview using the 4 different qHNMR methods to determine percent purity of an NMR sample. Knowing the percent purity is useful for measuring how much of a final product is pure. Conversely, the percent purity can determine the amount of impurity present in a final product.
I decided to make a video about qHNMR because I could not find any videos covering the 4 methods anywhere on YouTube or Google. A previous video I made utilized the 100% method. Although I gave a lengthy overview of the method, I felt I did not give it my best explanation, as it may have left many confused (link to the video: Synthesis of Virstatin and Purity Ana...).
So to enhance that video and give the 100% method proper justice, I wanted to make this video as reference for those who are confused or have trouble finding the correct values for the formulas in each of the 4 methods.
Yes, it is a loooong video (originally, it was over 1 hour before I did the editing) but here are some timestamps:
100% Method (6:08)
Internal Calibrant Method (19:08)
External Calibrant Method (24:33)
ECIC Method (28:58)
This video provides an overview using the 4 different qHNMR methods to determine percent purity of an NMR sample. Knowing the percent purity is useful for measuring how much of a final product is pure. Conversely, the percent purity can determine the amount of impurity present in a final product.
I decided to make a video about qHNMR because I could not find any videos covering the 4 methods anywhere on YouTube or Google. A previous video I made utilized the 100% method. Although I gave a lengthy overview of the method, I felt I did not give it my best explanation, as it may have left many confused (link to the video: Synthesis of Virstatin and Purity Ana...).
So to enhance that video and give the 100% method proper justice, I wanted to make this video as reference for those who are confused or have trouble finding the correct values for the formulas in each of the 4 methods.
Yes, it is a loooong video (originally, it was over 1 hour before I did the editing) but here are some timestamps:
100% Method (6:08)
Internal Calibrant Method (19:08)
External Calibrant Method (24:33)
ECIC Method (28:58)
6 سال پیش
در تاریخ 1397/06/11 منتشر شده
است.
13,303
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