Michigan sheep breeders aim to cure Huntington's disease
4.1 هزار بار بازدید -
9 سال پیش
-
Allegan County farmers Mike Ludlam
Allegan County farmers Mike Ludlam and Dr. Heather Ludlam, DVM, are on the frontlines of finding a potential treatment to cure Huntington’s disease, a fatal genetic disorder that progressively breaks down nerve cells in the brain and deteriorates a person’s physical and mental abilities.
The battle is personal for the couple. Mike’s adopted sister suffered and died from the devastating disease in 2012.
At Windswept Farms in Hopkins, the Ludlams manage a conventional sheep flock and breed lambs with GM1 gangliosidosis, a genetic disorder in which the lambs produce an overabundance of GM1 ganglioside, a naturally occurring trait which helps to protect brain cells.
People with Huntington’s disease are deficient in GM1 ganglioside, so the specially bred lambs could be a source for GM1 ganglioside production.
The Ludlams have initial approval from the U. S. Food and Drug Administration to conduct research, which they hope will move ovine GM1 ganglioside into clinical trials so it can be approved for pharmaceutical use to treat Huntington’s disease.
Learn more about how the Ludlams and other sheep producers are raising sheep conventionally for GM1 ganglioside research and clinical development at Glycoscience Research Inc., http://www.glycoscienceresearch.com/.
The battle is personal for the couple. Mike’s adopted sister suffered and died from the devastating disease in 2012.
At Windswept Farms in Hopkins, the Ludlams manage a conventional sheep flock and breed lambs with GM1 gangliosidosis, a genetic disorder in which the lambs produce an overabundance of GM1 ganglioside, a naturally occurring trait which helps to protect brain cells.
People with Huntington’s disease are deficient in GM1 ganglioside, so the specially bred lambs could be a source for GM1 ganglioside production.
The Ludlams have initial approval from the U. S. Food and Drug Administration to conduct research, which they hope will move ovine GM1 ganglioside into clinical trials so it can be approved for pharmaceutical use to treat Huntington’s disease.
Learn more about how the Ludlams and other sheep producers are raising sheep conventionally for GM1 ganglioside research and clinical development at Glycoscience Research Inc., http://www.glycoscienceresearch.com/.
9 سال پیش
در تاریخ 1394/10/21 منتشر شده
است.
4,195
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