Improving the treatment of low-risk MDS: luspatercept, treatment sequencing & disease classification

Andrew Brunner, MD, Massachusetts General Hospital, Boston, MA, discusses avenues for classifying and treating patients with low-risk myelodysplastic syndromes (LR-MDS). Dr Brunner highlights the erythroid maturation agent luspatercept, which was demonstrated to be effective in a press release on the Phase III COMMANDS study (NCT03682536). Dr Brunner further notes the importance of properly classifying patients with truly low-risk disease and improving the sequencing of therapies for this group. This interview took place at the 17th International Congress on Myelodysplastic Syndromes (MDS) 2023, held in Marseille, France.

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• #ring_sideroblasts