2017 Nobel Prize for Circadian Rhythm Explained

Are you pumped about the 2017 Nobel Prize in Physiology or Medicine? Me too! Learn all about the work and why it was so impressive that it got the Nobel Prize! This video comes complete with fruit flies, molecular mechanisms, and a special history on molecular biology. Exciting stuff.



Discussion on the molecular basis for the circadian rhythm in fruit flies from:

1. Siwicki, Eastman, Petersen, Rosbash, and Hall. “Antibodies to the period gene product of Drosophila reveal diverse tissue distribution and rhythmic changes in the visual system” Neuron (1988). https://doi.org/10.1016/0896-6273(88)...

2. Liu, Zwiebel, Hinton, Benzer, Hall, and Rosbash. “The period gene encodes a predominantly nuclear protein in adult Drosophila” Journal of Neuroscience (1992). http://www.jneurosci.org/content/jneu...

3. Vosshall, Price, Sehgal, Saez, and Young. “Block in nuclear localization of period protein by a second clock mutation, timeless” Science (1994). https://doi.org/10.1126/science.8128247

4. Price, Blau, Rothenfluh, Abodeely, Kloss, and Young. “double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation” Cell (1998). http://dx.doi.org/10.1016/S0092-8674(...


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Music:
"Odyssey" Kevin MacLeod (incompetech.com)
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"Twisted" Kevin MacLeod (incompetech.com)
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