Glucose transporters (GLUT) Animation: Usmle Medical Biochemistry
53.3 هزار بار بازدید -
5 سال پیش
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📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- Instagram: drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Glucose Transport
All GLUT transporters work via facilitated diffusion
GLUT1: most cell types including RBCs and brain
GLUT2 (bidirectional): pancreatic β islet cells, liver, renal tubular cells, small intestine
Low affinity and high capacity isoform – liver needs to be glycogen/glucose reservoir, but shouldn’t compete with other tissues
This should look similar to glucokinase (low affinity or ↑ Km and high capacity or ↑ Vmax) because it has a similar tissue distribution
GLUT3: neurons, testes, and the placenta
GLUT4: adipose tissue and striated muscle (skeletal and cardiac)
Insulin regulates insertion of GLUT4 transporters into cell membrane in response to high glucose levels
#glucosetransporters #transportationofglucose #glucosetransport #medicalbiochemistry #carbohydratemetabolism #GLUT #GLUT4 #GLUT2 #GLUT1 #fmge #medicalstudents #neetpg #medicalcollege #mbbslectures #usmleprep #nationalexitexam #nationalexittest #usmlestep1
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Glucose Transport
All GLUT transporters work via facilitated diffusion
GLUT1: most cell types including RBCs and brain
GLUT2 (bidirectional): pancreatic β islet cells, liver, renal tubular cells, small intestine
Low affinity and high capacity isoform – liver needs to be glycogen/glucose reservoir, but shouldn’t compete with other tissues
This should look similar to glucokinase (low affinity or ↑ Km and high capacity or ↑ Vmax) because it has a similar tissue distribution
GLUT3: neurons, testes, and the placenta
GLUT4: adipose tissue and striated muscle (skeletal and cardiac)
Insulin regulates insertion of GLUT4 transporters into cell membrane in response to high glucose levels
#glucosetransporters #transportationofglucose #glucosetransport #medicalbiochemistry #carbohydratemetabolism #GLUT #GLUT4 #GLUT2 #GLUT1 #fmge #medicalstudents #neetpg #medicalcollege #mbbslectures #usmleprep #nationalexitexam #nationalexittest #usmlestep1
5 سال پیش
در تاریخ 1398/12/15 منتشر شده
است.
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