Glucose transporters

This is a short overview of glucose transporters.

Information was adapted from TrueLearn, UWorld, and WIkipedia.  Images were adapted from Wikimedia Commons: Adapted from TrueLearn, Wikipedia
By Luuis12321 - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index...

ADDITIONAL TAGS:
Elevated serum glucose levels → insulin secreted from pancreatic beta-cells in islets of Langerhans → insulin binds to insulin receptors → mobilizes GLUT to cellular membrane → glucose absorption into tissues → lowers serum glucose level
GLUTs
Location: organ, tissue, cells
Features
1
Most cells, cornea, CNS, RBCs, placenta, fetal tissues
High affinity for glucose
2
Hepatocytes, kidneys, pancreatic β-cells, small intestines
Bidirectional transporter
High capacity, low affinity for glucose
3
Most cells, CNS, placenta
High affinity for glucose
4
Adipocytes, striated muscle (cardiac muscle, skeletal muscle)
Only insulin-dependent GLUT
Insulin stimulates incorporation into the membrane
5
Kidneys, small intestines, spermatocytes
Fructose transporter