7- BIOCHEMISTRY |GLYCOLYSIS | HEXOKINASE VS GLUCOKINASE
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4 سال پیش
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Glycolysis pathway: The glycolysis pathway
Glycolysis pathway:
The glycolysis pathway (pathway involved in breakdown of glucose) starting with glucose uptake into the cell glucose entrapment via hexokinase/glucokinase examining the energy consuming steps and finally the energy producing steps of the glycolysis pathway ending in pyruvate NADH and ATP production.
I also explain the difference between hexokinase and glucokinase the regulated irreversible steps of glycolysis along with what regulates the glycolysis pathway and easy ways to remember the irreversible steps and where ATP is produced in the pathway.
Hexokinase refers to any of a group of enzymes that accelerate the phosphorylation of hexoses (as in the formation of glucose-6-phosphate from glucose and ATP) in carbohydrate metabolism while glucokinase refers to a hexokinase found especially in the liver which catalyzes the phosphorylation of glucose in metabolic processes.
Found in
Hexokinase is found in each metabolizing cell in the body while glucokinase is only found in liver cells and β-pancreatic cells.
Type of Substrate
Furthermore hexokinase acts upon hexose sugars including glucose while glucokinase acts only on glucose.
Importance
Besides hexokinase is involved in the production of energy in normal cells while glucokinase reduces glycolysis in liver cells.
Effect of Insulin
Further on the insulin has no effect on hexokinase while insulin stimulates glucokinase.
Conclusion
Hexokinase is an enzyme found in all living cells involved in the phosphorylation of glucose. On the other hand glucokinase is a type of hexokinase only found in the liver. Hexokinase has a high affinity towards glucose while glucokinase has a low affinity towards glucose. Therefore hexokinase helps in glycolysis in normal cells while glucokinase facilitates glycogenesis in the liver. The main difference between hexokinase and glucokinase is the cellular localization and the role.
#hexokinasevsglucokinase #hexokinase #glucokinase #glycolysis.
The glycolysis pathway (pathway involved in breakdown of glucose) starting with glucose uptake into the cell glucose entrapment via hexokinase/glucokinase examining the energy consuming steps and finally the energy producing steps of the glycolysis pathway ending in pyruvate NADH and ATP production.
I also explain the difference between hexokinase and glucokinase the regulated irreversible steps of glycolysis along with what regulates the glycolysis pathway and easy ways to remember the irreversible steps and where ATP is produced in the pathway.
Hexokinase refers to any of a group of enzymes that accelerate the phosphorylation of hexoses (as in the formation of glucose-6-phosphate from glucose and ATP) in carbohydrate metabolism while glucokinase refers to a hexokinase found especially in the liver which catalyzes the phosphorylation of glucose in metabolic processes.
Found in
Hexokinase is found in each metabolizing cell in the body while glucokinase is only found in liver cells and β-pancreatic cells.
Type of Substrate
Furthermore hexokinase acts upon hexose sugars including glucose while glucokinase acts only on glucose.
Importance
Besides hexokinase is involved in the production of energy in normal cells while glucokinase reduces glycolysis in liver cells.
Effect of Insulin
Further on the insulin has no effect on hexokinase while insulin stimulates glucokinase.
Conclusion
Hexokinase is an enzyme found in all living cells involved in the phosphorylation of glucose. On the other hand glucokinase is a type of hexokinase only found in the liver. Hexokinase has a high affinity towards glucose while glucokinase has a low affinity towards glucose. Therefore hexokinase helps in glycolysis in normal cells while glucokinase facilitates glycogenesis in the liver. The main difference between hexokinase and glucokinase is the cellular localization and the role.
#hexokinasevsglucokinase #hexokinase #glucokinase #glycolysis.
4 سال پیش
در تاریخ 1399/06/04 منتشر شده
است.
196
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