Fenofibrates to reduce cholesterol and body Fat
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Fenofibrate is used along with
Fenofibrate is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It works by increasing the natural substance (enzyme) that breaks down fats in the blood. Fenofibrate belongs to a group of drugs known as "fibrates." Lowering triglycerides in people with very high triglyceride blood levels may decrease the risk of pancreas disease (pancreatitis). However, fenofibrate might not lower your risk of a heart attack or stroke. Talk to your doctor about the risks and benefits of fenofibrate.In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.
Although fibrates in general (including fenofibrate) are effective at lowering levels of triglycerides, VLDL cholesterol, total cholesterol, and apolipoprotein C-III, they do not appear to reduce the risk of cardiovascular events or cardiovascular/non-cardiovascular mortality, even when used in combination with a statin.
Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.
Usual Adult Dose of Fenofibrate for Hyperlipoproteinemia Type IIa (Elevated LDL):
Tricor: 145 mg orally once a day.
Lofibra and others: 160 mg to 200 mg orally once a day with food.
Antara: 130 mg orally once a day.
Triglide: 160 mg orally once a day.
Lipofen: 150 mg orally once a day with food.
Fenoglide: 120 mg orally once a day with food.
Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL):
Tricor: 145 mg orally once a day.
Lofibra and others: 160 mg to 200 mg orally once a day with food.
Antara: 130 mg orally once a day.
Triglide: 160 mg orally once a day.
Lipofen: 150 mg orally once a day with food.
Fenoglide: 120 mg orally once a day with food.
Usual Adult Dose of Fenofibrate for Hyperlipoproteinemia Type IV (Elevated VLDL):
Tricor: 48 to 145 mg orally once a day.
Lofibra and others: 54 mg to 200 mg orally once a day with food.
Antara: 43 mg to 130 mg orally once a day.
Triglide: 50 mg to 160 mg orally once a day.
Lipofen: 50 mg to 150 mg orally once a day with food.
Fenoglide: 40 mg to 120 mg orally once a day with food.
Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL):
Tricor: 48 to 145 mg orally once a day.
Lofibra and others: 54 mg to 200 mg orally once a day with food.
Antara: 43 mg to 130 mg orally once a day.
Triglide: 50 mg to 160 mg orally once a day.
Lipofen: 50 mg to 150 mg orally once a day with food.
Fenoglide: 40 mg to 120 mg orally once a day with food.
Usual Geriatric Dose of Fenofibrate for Hyperlipoproteinemia:
Tricor: 48 mg orally once a day. Increases in dosage should occur only after evaluating the effects on renal function and lipid levels at this dose, with a maximum recommended dose of 145 mg/24 hours.
Lofibra and others: 54 mg to 67 mg orally once a day with food. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Antara: 43 mg orally once a day. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Triglide: 50 mg orally once a day. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Lipofen: 50 mg orally once a day with food. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Fenoglide: 40 mg to 120 mg orally once a day with food
Although fibrates in general (including fenofibrate) are effective at lowering levels of triglycerides, VLDL cholesterol, total cholesterol, and apolipoprotein C-III, they do not appear to reduce the risk of cardiovascular events or cardiovascular/non-cardiovascular mortality, even when used in combination with a statin.
Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.
Usual Adult Dose of Fenofibrate for Hyperlipoproteinemia Type IIa (Elevated LDL):
Tricor: 145 mg orally once a day.
Lofibra and others: 160 mg to 200 mg orally once a day with food.
Antara: 130 mg orally once a day.
Triglide: 160 mg orally once a day.
Lipofen: 150 mg orally once a day with food.
Fenoglide: 120 mg orally once a day with food.
Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL):
Tricor: 145 mg orally once a day.
Lofibra and others: 160 mg to 200 mg orally once a day with food.
Antara: 130 mg orally once a day.
Triglide: 160 mg orally once a day.
Lipofen: 150 mg orally once a day with food.
Fenoglide: 120 mg orally once a day with food.
Usual Adult Dose of Fenofibrate for Hyperlipoproteinemia Type IV (Elevated VLDL):
Tricor: 48 to 145 mg orally once a day.
Lofibra and others: 54 mg to 200 mg orally once a day with food.
Antara: 43 mg to 130 mg orally once a day.
Triglide: 50 mg to 160 mg orally once a day.
Lipofen: 50 mg to 150 mg orally once a day with food.
Fenoglide: 40 mg to 120 mg orally once a day with food.
Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL):
Tricor: 48 to 145 mg orally once a day.
Lofibra and others: 54 mg to 200 mg orally once a day with food.
Antara: 43 mg to 130 mg orally once a day.
Triglide: 50 mg to 160 mg orally once a day.
Lipofen: 50 mg to 150 mg orally once a day with food.
Fenoglide: 40 mg to 120 mg orally once a day with food.
Usual Geriatric Dose of Fenofibrate for Hyperlipoproteinemia:
Tricor: 48 mg orally once a day. Increases in dosage should occur only after evaluating the effects on renal function and lipid levels at this dose, with a maximum recommended dose of 145 mg/24 hours.
Lofibra and others: 54 mg to 67 mg orally once a day with food. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Antara: 43 mg orally once a day. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Triglide: 50 mg orally once a day. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Lipofen: 50 mg orally once a day with food. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.
Fenoglide: 40 mg to 120 mg orally once a day with food
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در تاریخ 1403/04/12 منتشر شده
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