Mediators of Inflammation: An Introduction

#immunology #inflammation #pathology

Microbes, necrotic cells or tissue injury could trigger the release of certain soluble factors, from inflammatory cells, endothelial cells or from plasma. These soluble factors, called mediators of inflammation, initiate and amplify the inflammatory response and determine the consequent clinical and pathologic manifestations.

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References and further reading:
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins Basic Pathology. 10th ed. Elsevier; 2018.
💡Abbas AK, Litchman AH, Pillai S. Cellular and Molecular Immunology. 8th Edition. Saunders Elsevier; 2015.
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran – Pathologic Basis of Disease. 8th Edition. Saunders Elsevier; 2010.

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