The Case for Topical Anti-Androgens in Hair Loss
1.9 هزار بار بازدید -
11 ماه پیش
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Want to contact me?
Follow this: linktr.ee/kwxsoc
➤Have hair loss questions? Send me an email at "[email protected]"
➤ For video 1-on-1 Consultation Booking: https://zcal.co/kwx
Timestamps:
0:14 The Pathogenesis of Androgenetic Alopecia (AGA)
2:33 Topical Anti-Androgens
8:02 RU-58841, Testosterone, DHT, Clascoterone
14:35 Topical antiandrogens to Combat Male Pattern Baldness
18:02 Personal comments on “Reflex-hyperandrogenicity”"Hyper-reflexandrogenicity?"
25:55 Final Thoughts
Videos:
1. Super Topical Minoxidil Compound: FDA Enchantments Only
Super Topical Minoxidil Compound: FDA...
2. GT20029: The 'CURE' to male pattern baldness?
GT20029: The 'CURE' to male pattern b...
3. SCUBE3 and GT20029: The Cure to Male Pattern Baldness
SCUBE3 and GT20029: The Cure to Male ...
4. GT20029 in Phase 2: Cure to Male Pattern Baldness
GT20029 in Phase 2: Cure to Male Patt...
5. RU-58841 Human Clinical Trials? + Chemical Lore: "No Systemic Absorption, Massive Hair Gains"
RU-58841 Human Clinical Trials? + Che...
6. Fluridil "DHT BLOCKER" male pattern baldness treatment: Nonsystemic Topical Anti-androgen
Fluridil "DHT BLOCKER" male pattern b...
7. Experimental Androgenetic Alopecia Treatments: Should you try them?
Experimental Androgenetic Alopecia Tr...
8. Topical Finasteride: Review – Should you try it? (Plus How finasteride works)
Video
Study links:
1. Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and tetrahydrogestrinone (THG)
https://pubmed.ncbi.nlm.nih.gov/16797...
2. Androgen Physiology: Receptor and Metabolic Disorders
https://www.ncbi.nlm.nih.gov/books/NB...
3. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
https://www.researchgate.net/publicat...
4. Mechanism of Androgenic Alopecia: addressing speculations through empirical evidences
https://www.researchgate.net/publicat...
5. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial
considerations, and ethics
https://www.ncbi.nlm.nih.gov/pmc/arti...
6. Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
https://pubmed.ncbi.nlm.nih.gov/31832...
7. Winlevi how it works
https://www.winlevi-hcp.com/how-it-works
8. Half Life
https://www.ncbi.nlm.nih.gov/books/NB...
9. Androgen
https://en.wikipedia.org/wiki/Androgen
10. Pharmacokinetics and Pharmacodynamics of Nonsteroidal Androgen Receptor Ligands
https://www.ncbi.nlm.nih.gov/pmc/arti...
11. Synthesis and Structure—Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
https://www.researchgate.net/publicat...
12. Androgen receptor antagonists (antiandrogens): structure-activity relationships
https://pubmed.ncbi.nlm.nih.gov/10637...
https://sci-hub.ee/10.2174/0929867003...
13. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques
https://pubmed.ncbi.nlm.nih.gov/97987...
14. Clascoterone
https://go.drugbank.com/drugs/DB12499
15. Efficacy and Safety of Topical Clascoterone Cream, 1%, for Treatment in Patients With Facial Acne: Two Phase 3 Randomized Clinical Trials
https://www.researchgate.net/publicat...
16. COSMO ANNOUNCES THE BEGINNING OF THE PHASE III TRIALS IN MALES FOR THE TREATMENT OF ANDROGENETIC ALOPECIA
https://docs.google.com/document/d/1o...
17. Cortexolone 17α-propionate (Clascoterone) Is a Novel Androgen Receptor Antagonist that Inhibits Production of Lipids and Inflammatory Cytokines from Sebocytes In Vitro
https://pubmed.ncbi.nlm.nih.gov/31141...
18. Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with androgenetic alopecia
https://pubmed.ncbi.nlm.nih.gov/26636...
19. Twin Hair Loss - Dutasteride
https://web.archive.org/web/202001290...
20. Does anyone have the removed Breezula phase II 12 month baseline comparison results?
Reddit: does_anyone_have_the_removed_breezula_phase_ii_12
Want to contact me?
Follow this: linktr.ee/kwxsoc
➤Have hair loss questions? Send me an email at "[email protected]"
➤ For video 1-on-1 Consultation Booking: https://zcal.co/kwx
Timestamps:
0:14 The Pathogenesis of Androgenetic Alopecia (AGA)
2:33 Topical Anti-Androgens
8:02 RU-58841, Testosterone, DHT, Clascoterone
14:35 Topical antiandrogens to Combat Male Pattern Baldness
18:02 Personal comments on “Reflex-hyperandrogenicity”"Hyper-reflexandrogenicity?"
25:55 Final Thoughts
Videos:
1. Super Topical Minoxidil Compound: FDA Enchantments Only
Super Topical Minoxidil Compound: FDA...
2. GT20029: The 'CURE' to male pattern baldness?
GT20029: The 'CURE' to male pattern b...
3. SCUBE3 and GT20029: The Cure to Male Pattern Baldness
SCUBE3 and GT20029: The Cure to Male ...
4. GT20029 in Phase 2: Cure to Male Pattern Baldness
GT20029 in Phase 2: Cure to Male Patt...
5. RU-58841 Human Clinical Trials? + Chemical Lore: "No Systemic Absorption, Massive Hair Gains"
RU-58841 Human Clinical Trials? + Che...
6. Fluridil "DHT BLOCKER" male pattern baldness treatment: Nonsystemic Topical Anti-androgen
Fluridil "DHT BLOCKER" male pattern b...
7. Experimental Androgenetic Alopecia Treatments: Should you try them?
Experimental Androgenetic Alopecia Tr...
8. Topical Finasteride: Review – Should you try it? (Plus How finasteride works)
Video
Study links:
1. Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and tetrahydrogestrinone (THG)
https://pubmed.ncbi.nlm.nih.gov/16797...
2. Androgen Physiology: Receptor and Metabolic Disorders
https://www.ncbi.nlm.nih.gov/books/NB...
3. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
https://www.researchgate.net/publicat...
4. Mechanism of Androgenic Alopecia: addressing speculations through empirical evidences
https://www.researchgate.net/publicat...
5. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial
considerations, and ethics
https://www.ncbi.nlm.nih.gov/pmc/arti...
6. Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
https://pubmed.ncbi.nlm.nih.gov/31832...
7. Winlevi how it works
https://www.winlevi-hcp.com/how-it-works
8. Half Life
https://www.ncbi.nlm.nih.gov/books/NB...
9. Androgen
https://en.wikipedia.org/wiki/Androgen
10. Pharmacokinetics and Pharmacodynamics of Nonsteroidal Androgen Receptor Ligands
https://www.ncbi.nlm.nih.gov/pmc/arti...
11. Synthesis and Structure—Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
https://www.researchgate.net/publicat...
12. Androgen receptor antagonists (antiandrogens): structure-activity relationships
https://pubmed.ncbi.nlm.nih.gov/10637...
https://sci-hub.ee/10.2174/0929867003...
13. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques
https://pubmed.ncbi.nlm.nih.gov/97987...
14. Clascoterone
https://go.drugbank.com/drugs/DB12499
15. Efficacy and Safety of Topical Clascoterone Cream, 1%, for Treatment in Patients With Facial Acne: Two Phase 3 Randomized Clinical Trials
https://www.researchgate.net/publicat...
16. COSMO ANNOUNCES THE BEGINNING OF THE PHASE III TRIALS IN MALES FOR THE TREATMENT OF ANDROGENETIC ALOPECIA
https://docs.google.com/document/d/1o...
17. Cortexolone 17α-propionate (Clascoterone) Is a Novel Androgen Receptor Antagonist that Inhibits Production of Lipids and Inflammatory Cytokines from Sebocytes In Vitro
https://pubmed.ncbi.nlm.nih.gov/31141...
18. Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with androgenetic alopecia
https://pubmed.ncbi.nlm.nih.gov/26636...
19. Twin Hair Loss - Dutasteride
https://web.archive.org/web/202001290...
20. Does anyone have the removed Breezula phase II 12 month baseline comparison results?
Reddit: does_anyone_have_the_removed_breezula_phase_ii_12
11 ماه پیش
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